ERB-041, a selective ERβ agonist, inhibits iNOS production in LPS-activated peritoneal macrophages of endometriosis via suppression of NF-κB activation

Wang Xiu-li, Xiuli Wang, Cheng Wen-jun, Wenjun Cheng, Huihua Dai, Dai Hui-hua, Suping Han, Han Su-ping, Shilong Fu, Fu Shi-long
Molecular immunology · 2009 · vol. 46(11-12) , pp. 2413–2418 · doi:10.1016/j.molimm.2009.04.014 · PMID:19447495 · W2062557757
article OA: closed CC0 ⤵ 16 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

ERB-041, a selective ERβ agonist, was found to inhibit inducible nitric oxide synthase (iNOS) production in lipopolysaccharide (LPS)-activated peritoneal macrophages from endometriosis patients by suppressing NF-κB activation.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Anti-Inflammatory Agents, Non-Steroidal Endometriosis Estrogen Receptor beta Macrophages, Peritoneal NF-kappa B Nitric Oxide Synthase Type II Oxazoles Anti-Inflammatory Agents, Non-Steroidal Cells, Cultured Endometriosis Endometriosis Endometriosis Estrogen Receptor beta Estrogen Receptor beta Extracellular Signal-Regulated MAP Kinases Extracellular Signal-Regulated MAP Kinases Female Humans Lipopolysaccharides Lipopolysaccharides

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License: CC0 · commercial use OK