Reproducibility archive for manuscript 623972: histone-cluster and prespecified ion-channel transcriptomic analyses in endometriosis

Xinyue Cui, Jiaxuan Liu, Shengwu Wang, Huali Xu, Yali Fang, Guiping Wan, Rui Rui, Hong Zhu
2026 · doi:10.5281/zenodo.22097724 · W7204198643
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⚙ AI-generated summary by qwen3.7-flash, 2026-08-31 ⓘ

This reproducibility archive for endometriosis manuscript 623972 provides auditable workflows, scripts, and data for histone-cluster and ion-channel transcriptomic analyses to verify findings and exclude unreproducible legacy results.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-29 · read from full text ⓘ

This reproducibility archive supports the revised analysis of manuscript 623972 by providing auditable workflows for histone-cluster and prespecified ion-channel transcriptomic studies. The package includes processed expression data from datasets GSE51981 and GSE153739, along with scripts, logs, and decision rules to ensure transparency in proliferation and menstrual-phase sensitivity analyses. Legacy differential-expression results that could not be reproduced are explicitly excluded from verified findings to maintain statistical rigor. This paper is centrally about endometriosis — specifically involving transcriptomic analyses of histone clusters and ion channels within endometriosis tissue samples.

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Abstract

inal reproducibility archive supporting the revised analysis of manuscript 623972. The archive contains auditable GSE51981 and GSE153739 processed-expression workflows, proliferation and menstrual-phase sensitivity analyses, targeted histone-rich pathway analyses, and a pre-specified confirmatory ion-channel analysis with frozen gene sets and decision rules. It includes input matrices, analysis scripts, exact output tables including negative results, session information, run logs, the pre-specification and deviations log, and SHA256 checksums. Legacy differential-expression results that could not be reproduced from a documented statistical pipeline are not treated as verified findings in the revised manuscript.
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Reproducibility archive for manuscript 623972: histone-cluster and prespecified ion-channel transcriptomic analyses in endometriosis Authors/Creators Description inal reproducibility archive supporting the revised analysis of manuscript 623972. The archive contains auditable GSE51981 and GSE153739 processed-expression workflows, proliferation and menstrual-phase sensitivity analyses, targeted histone-rich pathway analyses, and a pre-specified confirmatory ion-channel analysis with frozen gene sets and decision rules. It includes input matrices, analysis scripts, exact output tables including negative results, session information, run logs, the pre-specification and deviations log, and SHA256 checksums. Legacy differential-expression results that could not be reproduced from a documented statistical pipeline are not treated as verified findings in the revised manuscript. Files 623972_FINAL_REPRODUCIBILITY_ARCHIVE (1).zip Files (74.0 MB) | Name | Size | Download all | |---|---|---| | md5:dbadda7980bf52dd8008e7aa93034979 | 74.0 MB | Preview Download |

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