Danazol for treatment of refractory autoimmune hemolytic anaemia

A M Tan, Angelina Tan, Jing-Xing Lou, J Lou, H K Cheng, Hong Cheng
Annals of the Academy of Medicine, Singapore · 1989 · vol. 18(6) , pp. 707–9 · PMID:2624421 · W32337753
Case report OA: closed CC0 ⤵ 2 in-corpus citations
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This case study reports that danazol achieved excellent hematological remission in a pediatric patient with severe autoimmune hemolytic anemia refractory to steroids and splenectomy.

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Abstract

Autoimmune hemolytic anemia (AHA) is uncommon in childhood. A female child presented with severe and chronic clinical course. She was refractory to steroid and the response to splenectomy was poor. She showed excellent remission of hematological condition with Danazol. Danazol may be the drug of choice for refractory autoimmune hemolytic anemia.

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MeSH descriptors

Anemia, Hemolytic, Autoimmune Danazol Pregnadienes Anemia, Hemolytic, Autoimmune Anemia, Hemolytic, Autoimmune Danazol Female Humans Infant Prednisolone Prednisolone Pregnadienes Splenectomy

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License: CC0 · commercial use OK