After superovulation-intrauterine insemination fails: the prognosis for treatment by gamete intrafallopian transfer/pronuclear stage transfer

Deirdre Robinson; D Robinson; C H Syrop; Craig H. Syrop; D G Hammitt; Diane G. Hammitt

doi:10.1016/s0015-0282(16)54908-5

After superovulation-intrauterine insemination fails: the prognosis for treatment by gamete intrafallopian transfer/pronuclear stage transfer

Deirdre Robinson, D Robinson, C H Syrop, Craig H. Syrop, D G Hammitt, Diane G. Hammitt

Fertility and sterility · 1992 · vol. 57(3) , pp. 606–612 · doi:10.1016/s0015-0282(16)54908-5 · PMID:1740206 · W55607995

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This paper examined the success rates of gamete intrafallopian transfer or pronuclear stage transfer following failed superovulation-intrauterine insemination treatments.

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Abstract

OBJECTIVE: To determine the prognosis for gamete intrafallopian transfer (GIFT)/pronuclear stage transfer (PROST) treatment after prior superovulation-intrauterine insemination (IUI). DESIGN: Matched, retrospective. SETTING: Outpatient university endocrine-infertility program. PATIENTS, PARTICIPANTS: One hundred forty-four women matched for infertility factors and age were studied according to the following three treatment groups: superovulation-IUI only, GIFT/PROST only, or GIFT/PROST after superovulation-IUI. MAIN OUTCOME MEASURES: Per cycle and cumulative pregnancy rates (PRs) were compared utilizing life table analysis. RESULTS: Cumulative PRs (0.408) for superovulation-IUI only were lower than initial (0.469) and cumulative (0.802) cycle fecundity of GIFT/PROST (P = 0.002). Per cycle and cumulative PRs did not differ between GIFT/PROST only versus GIFT/PROST after superovulation-IUI. CONCLUSIONS: Gamete intrafallopian transfer/PROST may be cost-effective when compared with superovulation-IUI. The prognosis for GIFT/PROST success is not negatively affected by earlier superovulation-IUI treatment failure.

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MeSH descriptors

Gamete Intrafallopian Transfer Insemination, Artificial Reproductive Techniques Superovulation Adult Female Humans Infertility, Female Infertility, Female Male Pregnancy Retrospective Studies Treatment Outcome Uterus

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Cites (3)

References (26)

Intrauterine insemination and ovulation stimulation as treatment of infertility via openalex
Life table analysis of intrauterine insemination pregnancy rates via openalex
The influence of infertility etiology on the outcome of IVF-ET and GIFT treatments via openalex
doi:10.1016/s0015-0282(16)54168-5 via openalex
doi:10.1016/s0015-0282(16)59543-0 via openalex
doi:10.1093/oxfordjournals.humrep.a136917 via openalex
doi:10.1016/s0015-0282(16)60136-x via openalex
doi:10.1016/s0015-0282(16)60073-0 via openalex
doi:10.1093/oxfordjournals.humrep.a137012 via openalex
doi:10.1016/s0015-0282(16)54050-3 via openalex
doi:10.1016/s0015-0282(16)60129-2 via openalex
doi:10.1016/s0015-0282(16)59414-x via openalex
doi:10.1016/s0015-0282(16)59052-9 via openalex
doi:10.1093/oxfordjournals.humrep.a137226 via openalex
doi:10.1016/s0015-0282(16)44120-8 via openalex
W6712571445 via openalex
W6715286291 via openalex
doi:10.1016/s0015-0282(16)59472-2 via openalex
doi:10.1016/s0015-0282(16)59583-1 via openalex
doi:10.1016/s0015-0282(16)59825-2 via openalex
doi:10.1016/0020-7292(92)90995-u via openalex
doi:10.1016/s0015-0282(16)48430-x via openalex
doi:10.1016/s0015-0282(16)54111-9 via openalex
doi:10.1007/bf01139186 via openalex
doi:10.1016/s0015-0282(16)48969-7 via openalex
doi:10.1016/0020-7292(88)90288-3 via openalex

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[1] The influence of infertility etiology on the outcome of IVF-ET and GIFT treatments 1990

[2] Intrauterine insemination and ovulation stimulation as treatment of infertility 1989

[3] Life table analysis of intrauterine insemination pregnancy rates 1988