[Interaction of blood sex steroid-binding globulin-steroid complexes with plasma membranes of human decidual endometrium cells]

N I Zhuk, Zhuk Ni, Avvakumov Gv, G V Avvakumov, O. A. Strel'chenok, Strel'chenok Oa
Biokhimiia (Moscow, Russia) · 1985 · vol. 50(7) , pp. 1105–7 · PMID:4041491 · W2409822760
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Plasma membranes of human decidual endometrium cells specifically bind sex steroid-binding globulin complexes with estrogens and danazol, indicating an active role for SBP in mediating steroid effects on target tissue.

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Abstract

Plasma membranes of decidual tissue cells specifically bind the sex steroid-binding globulin (SBP) complexes with estrogen (estradiol, estriol, estrone) and with the pharmacological agent danazol but do not interact with the SBP-testosterone or SBP-dihydrotestosterone complexes. The selectivity of interaction of the SBP-steroid complexes with decidual tissue cellular membranes provide evidence for the active role of SBP in the realization of steroid effects on the target tissue.

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MeSH descriptors

Decidua Estrogens Sex Hormone-Binding Globulin Cell Membrane Cell Membrane Danazol Danazol Decidua Estrogens Female Humans In Vitro Techniques Pregnancy Sex Hormone-Binding Globulin

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