Deep placentation

Robert Pijnenborg, Ivo Brosens, Jan J. Brosens, Roberto Romero
In: Placental Bed Disorders · 2010 · pp. 75–108 · doi:10.1017/cbo9780511750847.010 · W1556083524
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This chapter examines the deeper uterine anatomy, particularly the junctional zone's role in controlling uterine movements and its responsiveness to sex steroids.

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This chapter examines uterine deep anatomy with a focus on the junctional zone (JZ), describing it as a distinct, highly vascular compartment of myometrium that helps control uterine movements and is responsive to sex steroid levels. It reviews how the JZ undergoes cyclical changes that parallel endometrial thickness, the use of rapidly advancing imaging technologies to classify junctional zone contractions (JZC), and the fact that most existing data come from ultrasound in long-protocol IVF cycles. The chapter reports that excessive JZC are associated with reduced implantation rates in both spontaneous and stimulated cycles. It does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Placental Bed Disorders Buy print or eBook [Opens in a new window] Basic Science and its Translation to Obstetrics - Placental Bed Disorders - Placental Bed Disorders - Copyright page - Dedication - Contents - Contributors - Preface - Section 1: Introducing the placental bed - Section 2: Placental bed vascular disorders - Section 3: Uterine vascular environment - Section 4: Deep placentation - Section 5: Comparative anatomy and research models - Section 6: Genetics - Section 7: Risk factors, predictors, and future management - Section 8: Translation to obstetrics - Index Published online by Cambridge University Press: 06 July 2010 Book contents - Placental Bed Disorders - Placental Bed Disorders - Copyright page - Dedication - Contents - Contributors - Preface - Section 1: Introducing the placental bed - Section 2: Placental bed vascular disorders - Section 3: Uterine vascular environment - Section 4: Deep placentation - Section 5: Comparative anatomy and research models - Section 6: Genetics - Section 7: Risk factors, predictors, and future management - Section 8: Translation to obstetrics - Index This chapter deals with the deeper zonal anatomy of the uterus and particularly with the role these areas have in controlling uterine movements. The morphology of the junctional zone (JZ) suggests a distinct compartment of myometrium, tightly packed with muscle cells with an increased vascularity, designed as it were for a specific purpose. The JZ is responsive to changes in sex steroid levels, and undergoes a cycle of change which parallels the changes in endometrial thickness. Rapidly developing technology allows better images and the introduction of ever more complex classification of JZ contractions (JZC). The frequent use of ultrasound during assisted conception cycles provides most of the information we have about JZC, with most data coming from the study of long protocol stimulation in vitro fertilization (IVF) cycles. Excessive JZC have been shown to reduce implantation rates in both spontaneous and stimulated cycles. - Type - Chapter - Information - Placental Bed DisordersBasic Science and its Translation to Obstetrics, pp. 75 - 108Publisher: Cambridge University PressPrint publication year: 2010 Accessibility compliance for the HTML of this chapter is currently unknown and may be updated in the future. To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle. Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply. Find out more about the Kindle Personal Document Service. - Deep placentation - Book: Placental Bed Disorders - Online publication: 06 July 2010 To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox. - Deep placentation - Book: Placental Bed Disorders - Online publication: 06 July 2010 To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive. - Deep placentation - Book: Placental Bed Disorders - Online publication: 06 July 2010

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