Administration of medroxyprogesterone acetate after endomyometrial resection

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Endometrial resection for menorrhagia reduced menstrual flow in all 70 patients, with 50% achieving amenorrhea, and only two requiring hysterectomy postoperatively.

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Abstract

STUDY OBJECTIVE: To assess the efficacy of endometrial resection for treatment of menorrhagia in women to whom no preoperative agent was given to prepare the endometrium. DESIGN: Retrospective analysis of patients' records for all endometrial resections in which medroxyprogesterone acetate was used postoperatively. SETTING: Hospital day surgery unit. PATIENTS: Seventy patients with menorrhagia. INTERVENTIONS: The women underwent transvaginal sonography, followed by hysteroscopy and endometrial biopsy. The endometrium was removed using the 27F resectoscope followed by coagulation with the rollerball. Medroxy-progesterone acetate was prescribed for 2 months after surgery. MEASUREMENTS AND MAIN RESULTS: All women achieved a reduction in menstrual flow and 50% reported amenorrhea after endometrial resection. In only two was hysterectomy necessary due to recurrence of menorrhagia. CONCLUSION: Preoperative endometrial preparation was unnecessary when endometrial resection was carried out for treatment of menorrhagia. However, the patients received medroxyprogesterone acetate postoperatively.

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MeSH descriptors

Endometrium Medroxyprogesterone Acetate Menorrhagia Postoperative Complications Progesterone Congeners Adult Biopsy Endometrium Female Follow-Up Studies Humans Hysteroscopy Medroxyprogesterone Acetate Menorrhagia Menorrhagia Menorrhagia Middle Aged Postoperative Care Postoperative Care Postoperative Complications

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last seen: 2026-05-11T05:37:28.352103+00:00
pubmed
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License: CC0 · commercial use OK