Carcinosarcoma arising from uterine adenomyosis: A case report

Kaori Kiuchi, Kiyoshi Hasegawa, Anriko Kanamori, Hiromi Machida, Masaru Kojima, Ichio Fukasawa
Journal of Obstetrics and Gynaecology Research · 2015 · vol. 42(3) , pp. 358–362 · doi:10.1111/jog.12901 · PMID:26663238 · W2279263478
article OA: closed CC0 ⤵ 5 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report details a rare instance of carcinosarcoma with rhabdomyosarcomatous differentiation arising from uterine adenomyosis in a 56-year-old woman.

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Abstract

Carcinosarcoma arising from uterine adenomyosis is extremely rare. We encountered such a patient and herein provide a review of the literature. A 56-year-old woman was referred for a huge pelvic tumor, suspected to be an advanced uterine leiomyosarcoma. Intraoperative inspection revealed a mass, mainly located in the uterine myometrium, invading the uterine serosa. The tumor had previously spontaneously ruptured and disseminated to the pelvic cavity. Pathological and immunohistochemical examination revealed an infiltrative pattern of biphasic tumor cells composed of endometrioid adenocarcinoma and a nonepithelial component with rhabdomyosarcomatous differentiation. Benign endometrial glands with stromal cells were found adjacent to the area of the carcinosarcoma. The endometrium and both ovaries and fallopian tubes were microscopically free of tumor cells. The final diagnosis was heterologous type carcinosarcoma with rhabdomyosarcomatous differentiation, originating from uterine adenomyosis.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Carcinosarcoma Uterine Neoplasms Adenomyosis Carcinosarcoma Female Humans Middle Aged Uterine Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (18)

Cited by (5)

Source provenance

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