Primary endometrioid adenocarcinoma with coexisting endometrial tuberculosis. A case report

BACKGROUND: The most important cause of postmenopausal bleeding is endometrial cancer, whereas genital tuberculosis is uncommon in this age group. The association of these two disorders is extremely rare. CASE: Endometrial curettings performed on a 63-year-old woman with a bloody vaginal discharge and thickened endometrium disclosed complex atypical hyperplasia and granulomatous inflammation with caseation necrosis. The uterus contained a well-differentiated endometrial adenocarcinoma with squamous differentiation invading about one-half the myometrial thickness and granulomatous inflammation with caseation necrosis. The lymph nodes were free of disease. CONCLUSION: Although the coexistence of endometrial cancer and tuberculosis is extremely rare, it may occur in patients who live in the regions with a high prevalence of tuberculosis.