Intrauterine insemination as front-line treatment for non-tubal infertility

Michael Tucker, M J Tucker, C J Wong, Colleen Wong, Y. M. Chan, Milton Leong, M K Leong, Clement K. M. Leung, C K Leung
Asia-Oceania journal of obstetrics and gynaecology · 1990 · vol. 16(2) , pp. 137–143 · doi:10.1111/j.1447-0756.1990.tb00016.x · PMID:2378592 · W2030711027
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Intrauterine insemination (IUI) in non-tubal infertility patients, particularly when stimulated with ovulation induction agents, resulted in a 12% delivered/ongoing pregnancy rate per cycle.

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Abstract

Eighty-one clinical pregnancies occurred from 508 cycles of intrauterine insemination (IUI) in 242 patients. Following 20 miscarriages 30 pregnancies have been delivered, and 31 remain ongoing at 16 weeks and beyond. This represents a 12% delivered/ongoing pregnancy outcome per cycle of IUI, in women of average age 30.9 years who with their partners had suffered on average 3.65 years of infertility. All forms of non-tubal infertility were treated with pregnancies occurring in all primary categories. No pregnancies occurred in 5 women who underwent IUI in 18 natural cycles. All pregnancies arose in the 237 women who received clomiphene citrate, human menopausal gonadotropin, or a combination of both with ovulation triggered by human chorionic gonadotropin. Dependent upon patient age and duration of infertility, we implement IUI as a frontline treatment for all cases of non-tubal infertility prior to subjecting patients to the more costly and invasive tubal transfer techniques.

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Condition tags

infertility

MeSH descriptors

Infertility, Female Insemination, Artificial Insemination, Artificial, Homologous Adult Female Humans Infant, Newborn Insemination, Artificial Insemination, Artificial, Homologous Male Pregnancy Pregnancy, Multiple Uterus

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License: CC0 · commercial use OK