FEATURES OF DOPPLER INDICATORS OF UTERINE BLOOD FLOW IN PATIENTS WITH ADENOMYOSIS

Clinical medicine FEATURES OF DOPPLER INDICATORS OF UTERINE BLOOD FLOW IN PATIENTS WITH ADENOMYOSIS Published 2024-02-14 Authors: МA М.E. Azizova IM I.Sh. Magalov - Abstract: - The purpose of study was to establish the incidence, clinical and anamnestic features of patients with adenomyosis. A comprehensive clinical, laboratory and instrumental prospective examination was carried out on 224 patients aged 30 to 50 years (average age – 42.0±1.8 years) with adenomyosis. These patients constituted the main study group. Patients of the main group were divided into 2 subgroups depending on the form of adenomyosis (Group I – diffuse form – 106 women, Group II – nodular form – 118 women). The control group consisted of 84 relatively healthy women of reproductive age, with a regular ovulatory menstrual cycle and no history of gynecological diseases. The largest number of adenomyosis are registered in patients aged 36–40 years – 92 women, 41.1±3.3 %. The most common pathologies in patients with various forms of the adenomyosis were the diseases of the cervix (114 women, 50.89±3.3 %), uterine fibroids (113 women, 50.45±3.4 %) and inflammatory diseases of the pelvic organs (113 women, 50.45±3.4 %). Resistance index values in the follicular phase and luteal phase have statistically significant differences between groups of patients with adenomyosis (p<0.05). - Keywords: - adenomyosis diagnosis resistance index blood flow uterus differential diagnosis - References: - - Abrão MS, Andres MP, Barbosa RN, Bassi MA, Kho RM. Optimizing Perioperative Outcomes with Selective Bowel Resection Following an Algorithm Based on Preoperative Imaging for Bowel Endometriosis. J Minim Invasive Gynecol. 2020 May-Jun;27(4):883–891. doi: 10.1016/j.jmig.2019.06.010. - Artymuk N, Zotova O, Gulyaeva L. Adenomyosis: genetics of estrogen metabolism. Horm Mol Biol Clin Investig. 2019 Mar 15;37(2). doi: 10.1515/hmbci-2018-0069. - Dessouky R, Gamil SA, Nada MG, Mousa R, Libda Y. Management of uterine adenomyosis: current trends and uterine artery embolization as a potential alternative to hysterectomy. Insights Imaging. 2019 Apr 27;10(1):48. doi: 10.1186/s13244-019-0732-8. - Donnez O, Donnez J. Gonadotropin-releasing hormone antagonist (linzagolix): a new therapy for uterine adenomyosis. Fertil Steril. 2020 Sep;114(3):640–645. doi: 10.1016/j.fertnstert.2020.04.017. - Dueholm M. Minimally invasive treatment of adenomyosis. Best Pract Res Clin Obstet Gynaecol. 2018 Aug;51:119-137. doi: 10.1016/j.bpobgyn.2018.01.016. - Harada T, Khine YM, Kaponis A, Nikellis T, Decavalas G, Taniguchi F. The Impact of Adenomyosis on Women's Fertility. Obstet Gynecol Surv. 2016 Sep;71(9):557-68. doi: 10.1097/OGX.0000000000000346. - Hashimoto A, Iriyama T, Sayama S, Nakayama T, Komatsu A, Miyauchi A, et al. Adenomyosis and adverse perinatal outcomes: increased risk of second trimester miscarriage, preeclampsia, and placental malposition. J Matern Fetal Neonatal Med. 2018 Feb;31(3):364–369. doi: 10.1080/14767058.2017.1285895. - Khalifa MA, Atri M, Klein ME, Ghatak S, Murugan P. Adenomyosis As a Confounder to Accurate Endometrial Cancer Staging. Semin Ultrasound CT MR. 2019 Aug;40(4):358–363. doi: 10.1053/j.sult.2019.04.004. - Lazzeri L, Morosetti G, Centini G, Monti G, Zupi E, Piccione E, et al. A sonographic classification of adenomyosis: interobserver reproducibility in the evaluation of type and degree of the myometrial involvement. Fertil Steril. 2018 Nov;110(6):1154–1161.e3. doi: 10.1016/j.fertnstert.2018.06.031. - Orlova YuA, Hromova AM, Ketova OM, Liakhovska TYu, Martynenko VB, Krutikova EI. Aseptic inflammation as the essential link in the pathogenesis of endometrioid disease. Medicni perspektivi. 2023;28(3):55–61. https://doi.org/10.26641/2307-0404.2023.3.288961 - Osada H. Uterine adenomyosis and adenomyoma: the surgical approach. Fertil Steril. 2018 Mar;109(3):406-417. doi: 10.1016/j.fertnstert.2018.01.032. 12.Schrager S, Yogendran L, Marquez CM, Sadowski EA. Adenomyosis: Diagnosis and Management. Am Fam Physician. 2022 Jan 1;105(1):33–38. - Szubert M, Koziróg E, Olszak O, Krygier-Kurz K, Kazmierczak J, Wilczynski J. Adenomyosis and Infertility-Review of Medical and Surgical Approaches. Int J Environ Res Public Health. 2021 Jan 30;18(3):1235. doi: 10.3390/ijerph18031235. - Yu O, Schulze-Rath R, Grafton J, et al.; Adenomyosis incidence, prevalence and treatment: United States population-based study 2006 – 2015. Am J Obstet Gynecol. 2020;223(1):94.e1–94.e10. - Zhu J, Liu S, Gao D. Application of Color Doppler Ultrasound in Microscopic Imaging Diagnosis of Adenomyosis. Scanning. 2022 May 31;2022:2366871. doi: 10.1155/2022/2366871. - Publication: - «World of Medicine and Biology» Vol. 20 No. 87 (2024) , с. 11-15 УДК 618.14–006.514.01.01 How to Cite FEATURES OF DOPPLER INDICATORS OF UTERINE BLOOD FLOW IN PATIENTS WITH ADENOMYOSIS. (2024). World of Medicine and Biology, 20(87), 11-15. https://doi.org/10.26724/2079-8334-2024-1-87-11-15 Share