Methodological limitations in the diagnostic validation of P-C4BP-Rf for ovarian clear cell carcinoma versus endometrioma: addressing sample size constraints and selective bias

M Chen; Meibo Chen; Shanshan Yuan

doi:10.1016/j.cca.2025.120416

Methodological limitations in the diagnostic validation of P-C4BP-Rf for ovarian clear cell carcinoma versus endometrioma: addressing sample size constraints and selective bias

M Chen, Meibo Chen, Shanshan Yuan

Clinica chimica acta; international journal of clinical chemistry · 2025 · vol. 576 , pp. 120416 · doi:10.1016/j.cca.2025.120416 · PMID:40480434 · W4411021769

Other OA: closed CC0

Limited metadata. Only one source feed has indexed this record so far — no abstract, full text, or open-access copy is available through Endo Lab. The publisher's page (linked below) is the canonical location for the actual content. If you have institutional access, use "Find at my library".

View at publisher → View on OpenAlex View on PubMed

⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-13 ⓘ

This paper identifies methodological limitations, specifically sample size constraints and selective bias, in the diagnostic validation of P-C4BP-Rf for ovarian clear cell carcinoma versus endometrioma.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

endometrioma

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

Clinical usefulness of E4-phytohemagglutinin reactive C4-binding protein relative front value in serum for distinguishing between ovarian clear cell adenocarcinoma and endometrioma 2025

References (7)

Clinical usefulness of E4-phytohemagglutinin reactive C4-binding protein relative front value in serum for distinguishing between ovarian clear cell adenocarcinoma and endometrioma via openalex
W3155414971 via openalex
doi:10.1007/s13312-011-0055-4 via openalex
doi:10.1016/j.jclinepi.2014.02.008 via openalex
doi:10.4143/crt.2014.324 via openalex
doi:10.3390/cancers12123730 via openalex
doi:10.1002/sim.7993 via openalex

Source provenance

openalex: last seen: 2026-05-11T06:53:11.423351+00:00
pubmed: last seen: 2026-10-08T21:49:45.452123+00:00
unpaywall: last seen: 2026-10-18T06:28:46.490043+00:00

License: CC0 · commercial use OK

[1] Clinical usefulness of E4-phytohemagglutinin reactive C4-binding protein relative front value in serum for distinguishing between ovarian clear cell adenocarcinoma and endometrioma 2025