Pain catastrophizing and pain health-related quality-of-life in endometriosis

McPeak, Allison E., Allaire, Catherine, Williams, Christina, Albert, Arianne, Lisonkova, Sarka, Yong, Paul J.
2022 · doi:10.14288/1.0421292 · W6961241886
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This cross-sectional analysis of women with endometriosis found that higher pain catastrophizing was independently associated with worse pain health-related quality-of-life, independent of pain severity and other confounders.

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This cross-sectional study analyzed baseline data from 236 women at a tertiary referral center to determine if pain catastrophizing independently associates with pain health-related quality-of-life in endometriosis. Using multivariable linear regression to control for confounders such as demographic variables and comorbid conditions, the researchers found that higher levels of pain catastrophizing were significantly linked to worse pain health-related quality-of-life. The association remained significant even after adjusting for pain severity, dysmenorrhea intensity, and abdominal wall pain indicators. This paper is centrally about endometriosis — specifically examining psychological factors like pain catastrophizing and their impact on health-related quality-of-life in patients with the condition.

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Abstract

OBJECTIVES: To determine if pain catastrophizing is independently associated with pain health-related quality-of-life in women with endometriosis, independent of potential confounders. METHODS: Analysis of cross-sectional baseline data from a prospective database at a tertiary referral center for endometriosis/pelvic pain. Referrals to the center were recruited between December 2013 to April 2015, with data collected from online patient questionnaires, physical examination, and review of medical records. The primary outcome was health-related quality-of-life as measured by the 11-item pain subscale of the Endometriosis Health Profile-30 questionnaire. The Pain Catastrophizing Scale was the independent variable of interest. Other independent variables (potential confounders) included other psychological measures, pain severity, comorbid pain conditions, and social-behavioral and demographic variables. Multivariable linear regression was used to control for these potential confounders and assess independent associations with the primary outcome. RESULTS: 236 women were included (87% consent rate). The mean age was 35.0±7.3 years, and 98 (42%) had Stage I-II endometriosis, 110 (47%) had Stage III-IV endometriosis, and 28 (11%) were of unknown stage after review of operative records. Regression analysis demonstrated that higher pain catastrophizing (p<0.001), more severe chronic pelvic pain (p<0.001), more severe dysmenorrhea (p<0.001), and abdominal wall pain (positive Carnett test) (p=0.033) were independently associated with worse pain health-related quality-of-life. DISCUSSION: Higher pain catastrophizing was associated with a reduced pain health-related quality-of-life in women with endometriosis at a tertiary referral center, independent of pain severity and other potential confounders.
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Abstract

OBJECTIVES: To determine if pain catastrophizing is independently associated with pain health-related quality-of-life in women with endometriosis, independent of potential confounders. METHODS: Analysis of cross-sectional baseline data from a prospective database at a tertiary referral center for endometriosis/pelvic pain. Referrals to the center were recruited between December 2013 to April 2015, with data collected from online patient questionnaires, physical examination, and review of medical records. The primary outcome was health-related quality-of-life as measured by the 11-item pain subscale of the Endometriosis Health Profile-30 questionnaire. The Pain Catastrophizing Scale was the independent variable of interest. Other independent variables (potential confounders) included other psychological measures, pain severity, comorbid pain conditions, and social-behavioral and demographic variables. Multivariable linear regression was used to control for these potential confounders and assess independent associations with the primary outcome. RESULTS: 236 women were included (87% consent rate). The mean age was 35.0±7.3 years, and 98 (42%) had Stage I-II endometriosis, 110 (47%) had Stage III-IV endometriosis, and 28 (11%) were of unknown stage after review of operative records. Regression analysis demonstrated that higher pain catastrophizing (p<0.001), more severe chronic pelvic pain (p<0.001), more severe dysmenorrhea (p<0.001), and abdominal wall pain (positive Carnett test) (p=0.033) were independently associated with worse pain health-related quality-of-life. DISCUSSION: Higher pain catastrophizing was associated with a reduced pain health-related quality-of-life in women with endometriosis at a tertiary referral center, independent of pain severity and other potential confounders. Item Metadata | Title | Pain catastrophizing and pain health-related quality-of-life in endometriosis | | Creator | | | Contributor | | | Publisher | Wolters Kluwer Health, Inc. | | Date Issued | 2018 | | Description |

Objectives

To determine if pain catastrophizing is independently associated with pain health-related quality-of-life in women with endometriosis, independent of potential confounders. METHODS: Analysis of cross-sectional baseline data from a prospective database at a tertiary referral center for endometriosis/pelvic pain. Referrals to the center were recruited between December 2013 to April 2015, with data collected from online patient questionnaires, physical examination, and review of medical records. The primary outcome was health-related quality-of-life as measured by the 11-item pain subscale of the Endometriosis Health Profile-30 questionnaire. The Pain Catastrophizing Scale was the independent variable of interest. Other independent variables (potential confounders) included other psychological measures, pain severity, comorbid pain conditions, and social-behavioral and demographic variables. Multivariable linear regression was used to control for these potential confounders and assess independent associations with the primary outcome. RESULTS: 236 women were included (87% consent rate). The mean age was 35.0±7.3 years, and 98 (42%) had Stage I-II endometriosis, 110 (47%) had Stage III-IV endometriosis, and 28 (11%) were of unknown stage after review of operative records. Regression analysis demonstrated that higher pain catastrophizing (p<0.001), more severe chronic pelvic pain (p<0.001), more severe dysmenorrhea (p<0.001), and abdominal wall pain (positive Carnett test) (p=0.033) were independently associated with worse pain health-related quality-of-life. DISCUSSION: Higher pain catastrophizing was associated with a reduced pain health-related quality-of-life in women with endometriosis at a tertiary referral center, independent of pain severity and other potential confounders. | | Subject | | | Genre | | | Type | | | Language | eng | | Date Available | 2022-10-17 | | Provider | Vancouver : University of British Columbia Library | | Rights | Attribution-NonCommercial-NoDerivatives 4.0 International | | DOI | 10.14288/1.0421292 | | URI | | | Affiliation | | | Citation | McPeak, Allison E. MPH; Allaire, Catherine MD; Williams, Christina MD; Albert, Arianne PhD; Lisonkova, Sarka MD, PhD; Yong, Paul J. MD, PhD. Pain Catastrophizing and Pain Health-Related Quality-of-Life in Endometriosis. The Clinical Journal of Pain: April 2018 - Volume 34 - Issue 4 - p 349-356 | | Publisher DOI | 10.1097/AJP.0000000000000539 | | Peer Review Status | Reviewed | | Scholarly Level | Faculty; Researcher; Graduate | | Rights URI | | | Aggregated Source Repository | DSpace | Item Media Item Citations and Data Rights Attribution-NonCommercial-NoDerivatives 4.0 International

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