Gynecologic malignancies accompanied by benign hormone-dependent diseases

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AI-generated summary by claude@2026-06, 2026-06-09

Postmenopausal women with endometrial carcinomas showed a 1.5- to 2-fold higher prevalence of myoma uteri and adenomyosis uteri compared to a control group.

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Abstract

OBJECTIVE: To investigate the correlation between benign gynecologic diseases and hormone-dependent malignancies such as endometrial carcinoma in postmenopausal women. DESIGN: We retrospectively analyzed the prevalence of myoma uteri and adenomyosis uteri in 136 cases of endometrial carcinomas. We used 222 uterine prolapse cases as controls. RESULTS: The results showed that 21.6% and 9.9% of healthy postmenopausal women (control) had myoma uteri and adenomyosis uteri, respectively, after the cessation of menses. However, postmenopausal women with endometrial carcinomas had a 1.5- to 2-fold higher prevalence, respectively, for myoma uteri and adenomyosis uteri as compared with the postmenopausal control women. CONCLUSION: There was a higher prevalence of myoma uteri and adenomyosis uteri in postmenopausal patients with endometrial carcinomas than in the control population.

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Condition tags

mesh:D004715adenomyosis

MeSH descriptors

Endometrial Neoplasms Endometriosis Leiomyoma Postmenopause Uterine Neoplasms Aged Endometrial Neoplasms Endometriosis Female Humans Leiomyoma Middle Aged Retrospective Studies Uterine Neoplasms

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:13:24.901228+00:00
License: CC0 · commercial use OK