Adenomyosis and female fertility: A critical review of the evidence

Sesh Kamal Sunkara, S K Sunkara, Khalid S. Khan, K S Khan
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology · 2012 · vol. 32(2) , pp. 113–116 · doi:10.3109/01443615.2011.624208 · PMID:22296416 · W2106033595
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This review critically appraises evidence linking adenomyosis to female infertility and assesses treatment effectiveness, highlighting the need for larger studies and randomized trials.

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Abstract

Adenomyosis is frequent during the evaluation of infertile women. Present evidence suggests that adenomyosis has a negative impact on female fertility. Limited data from uncontrolled studies suggest that treatment of adenomyosis may improve fertility. This review critically appraises the existing evidence to determine the relationship between adenomyosis and female fertility. There is need for large epidemiological studies to substantiate the association between adenomyosis and infertility. Furthermore, if adenomyosis has a harmful impact on fertility there is a need to determine if its treatment improves fertility and the various treatment modalities reported need to be assessed for their effectiveness in randomised trials.

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Condition tags

mesh:D004715adenomyosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Animals Endometriosis Endometriosis Female Fertilization in Vitro Humans Infertility, Female Infertility, Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (40)

Cited by (20)

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