Gestogens and anti-gestogens as treatment of endometriosis

Eileen Thomas, Liselotte Mettler
In: Modern Approaches to Endometriosis · 1991 · pp. 221–238 · doi:10.1007/978-94-011-3864-2_12 · W32483892
book-chapter OA: closed CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This chapter will describe the role of gestagens and anti-gestagens, such as gestrinone, in treating endometriosis as first- and second-line drugs.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This chapter reviews the therapeutic role of gestagens (progestagens) and anti-gestagens in endometriosis, contrasting this history with the better-known development of danazol and LHRH analogues since the 1970s. It describes gestagens first and then focuses on anti-gestagens exemplified by gestrinone, discussing the place of these drug classes as first- and second-line options, while noting that other drug developments have overshadowed progestagens/anti-gestagens in the literature. The main limitation is that the text is a narrative account intended to situate these therapies rather than present new primary experimental results, and it points readers elsewhere for details on danazol and LHRH analogues. This paper is centrally about endometriosis — it is a chapter describing the place of gestogens/progestagens and anti-gestagens (especially gestrinone) in endometriosis treatment.

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endometriosis

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License: CC0 · commercial use OK