Dolor - Evaluación del potencial papel terapéutico de la inhibición de RANK en modelos optimizados de dolor e infertilidad asociados a endometriosis

Raúl Gómez
2021 · doi:10.5281/zenodo.15112956 · W6893383953
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This study evaluated the therapeutic potential of RANK inhibition in optimized mouse models to assess its impact on endometriosis-associated pain and infertility.

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This research dataset documents a project funded by the Instituto de Salud Carlos III to evaluate the therapeutic potential of RANK inhibition in optimizing models for pain and infertility associated with endometriosis. The study utilized optimized mouse models, specifically Von Frey tests on Balb-C and CB57 strains, to assess non-evoked pain through quantitative measures of distance and time. The experimental phase spanned from January 2021 to December 2024, focusing on preclinical validation of this specific molecular target within established endometriosis frameworks. This paper is centrally about endometriosis — specifically investigating the role of RANK inhibition as a therapeutic strategy for managing pain and infertility in this condition.

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Abstract

Dolor no evocado mediante test compartamentales cuantitativos de distancia y tiempo en modelo animal de ratón Von Freim, Balb-C y CB57 con endometriosis
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Published March 31, 2025 | Version 1 Dataset Open Dolor - Evaluación del potencial papel terapéutico de la inhibición de RANK en modelos optimizados de dolor e infertilidad asociados a endometriosis Description Dolor no evocado mediante test compartamentales cuantitativos de distancia y tiempo en modelo animal de ratón Von Freim, Balb-C y CB57 con endometriosis Files Readme.txt Files (4.6 MB) | Name | Size | Download all | |---|---|---| | md5:7fc46ce94f91400750c43778f89592b5 | 1.6 MB | Download | | md5:fe6bb829ac490b7c7635d418595b9cc3 | 1.1 MB | Download | | md5:1ca8819f0594c0533a7a8868f6080667 | 2.3 kB | Preview Download | | md5:966c5c0628470738e3c717cd629bf3c8 | 282.6 kB | Download | | md5:59b35597587808f4c5de1c7ad91bc5f0 | 298.5 kB | Download | | md5:89f676f2570eecaee9c9d1bc5b675389 | 285.2 kB | Download | | md5:f5c13bfee1db4d56b13b8ad4b62facd7 | 199.7 kB | Download | | md5:5593785bc6a20a855bb845cd63f96236 | 206.8 kB | Download | | md5:bbef81845b63c3740b62792e010482ad | 282.6 kB | Download | | md5:7bac21df6f56c3815d88e40a8c35adcf | 304.1 kB | Download | Additional details Identifiers Funding - Instituto de Salud Carlos III - Evaluación del potencial papel terapéutico de la inhibición de RANK en modelos optimizados de dolor e infertilidad asociados a endometriosis PI20/01835 Dates - Created - 2021-01-01Start of experimental phase - Created - 2024-12-31End of experimental phase

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endometriosis

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last seen: 2026-05-11T03:56:24.920043+00:00
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