Shrinkage of recurrent endometrioma, after danazol

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Danazol treatment reduced a recurrent 7 cm endometrioma to 3.3 cm in a patient with primary infertility, who subsequently conceived and delivered a healthy infant after discontinuing the medication.

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Abstract

A 29-year-old woman presented with a history of primary infertility one year after excision of endometrioma of the left ovary. On the first pelvic examination at the Infertility Clinic, the uterus was of normal size, retroversion and rather fixed with 0.5 cm firm nodule at its posterior surface. There was a tense cystic mass about 4-5 cm at the right adnexa. Three months later this mass was noted to have increased in size and the ultrasound revealed a slight, thick wall cystic mass with the largest diameter of 7 cm. The impression was endometriotic cyst of the right ovary. The patient was put on danazol 200 mg daily. After 6 months of treatment, the right ovarian mass was found to be 3.3 cm in the largest diameter by ultrasound. So the medication was discontinued. The patient conceived on the third cycle after discontinuing danazol. A healthy male infant, birth weight 3,320 g was delivered by elective cesarean section at term.

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Condition tags

endometriosisendometriomainfertility

MeSH descriptors

Danazol Endometriosis Neoplasm Recurrence, Local Ovarian Neoplasms Adult Adult Danazol Danazol Endometriosis Endometriosis Female Female Humans Humans Neoplasm Recurrence, Local Neoplasm Recurrence, Local Ovarian Cysts Ovarian Cysts Ovarian Cysts Ovarian Neoplasms

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Source provenance

europepmc
last seen: 2026-11-01T09:25:17.647243+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:06:23.467768+00:00
License: CC0 · commercial use OK