Endometriosis Unveiled: Innovations in Diagnosis and Management of Endometriosis

Hannah Millimet, Millimet H, Abigail Lee, Lee A, Courtney Lim, Lim C, Allaire C, Catherine Allaire, As-Sanie S, Sawsan As-Sanie
Clinical Obstetrics and Gynecology · 2026 · vol. 69(4) , pp. 378–388 · doi:10.1097/GRF.0000000000001045 · PMID:42442755
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-17 ⓘ

This review discusses current and future innovations in endometriosis diagnosis, including imaging, biomarkers, and AI, alongside updates on medical, surgical, and nonpharmaceutical management strategies.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-10-27 · read from full text ⓘ

This review article outlines the complex inflammatory and pain pathways associated with endometriosis, providing a comprehensive background on the condition's pathophysiology. It explores novel diagnostic approaches such as advanced imaging, biomarkers, and artificial intelligence integration alongside current medical and surgical management strategies. The authors also discuss emerging nonpharmaceutical interventions and future directions including precision medicine to improve patient care outcomes. This paper is centrally about endometriosis — specifically reviewing innovations in diagnosis, medical management, surgical techniques, and future therapeutic directions for the disease.

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Abstract

Endometriosis is a chronic inflammatory condition that can result in chronic pain through complex nociceptive, neuropathic, and nociplastic pathways. This article provides a comprehensive background on endometriosis as well as future directions in diagnosis and management. The diagnosis of endometriosis is explored, including novel imaging techniques, biomarkers, and the integration of artificial intelligence. The medical management of endometriosis is reviewed, including a focus on new nonhormonal treatment options. Surgical treatments are reviewed along with surgical outcomes. We discuss nonpharmaceutical and behavioral interventions with growing interest. Finally, this article reviews future directions in endometriosis care, including precision medicine and AI.
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Endometriosis Unveiled: Innovations in Diagnosis and Management of Endometriosis - Hannah Millimet* - Abigail Lee† - Courtney Lim* - Catherine Allaire† - Sawsan As-Sanie* Endometriosis is a chronic inflammatory condition that can result in chronic pain through complex nociceptive, neuropathic, and nociplastic pathways. This article provides a comprehensive background on endometriosis as well as future directions in diagnosis and management. The diagnosis of endometriosis is explored, including novel imaging techniques, biomarkers, and the integration of artificial intelligence. The medical management of endometriosis is reviewed, including a focus on new nonhormonal treatment options. Surgical treatments are reviewed along with surgical outcomes. We discuss nonpharmaceutical and behavioral interventions with growing interest. Finally, this article reviews future directions in endometriosis care, including precision medicine and AI.

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MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis

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