Systematic review and meta-analysis of reproductive outcomes after high-intensity focused ultrasound (HIFU) treatment of adenomyosis

Yishan Chen; Yi-Shan Chen; Shunhe Lin; Xi Xie; Jingsong Yi; Xishi Liu; Sun‐Wei Guo; Sun-Wei Guo

doi:10.1016/j.bpobgyn.2023.102433

Systematic review and meta-analysis of reproductive outcomes after high-intensity focused ultrasound (HIFU) treatment of adenomyosis

Yishan Chen, Yi-Shan Chen, Shunhe Lin, Xi Xie, Jingsong Yi, Xishi Liu, Sun‐Wei Guo, Sun-Wei Guo

Best practice & research. Clinical obstetrics & gynaecology · 2023 · vol. 92 , pp. 102433 · doi:10.1016/j.bpobgyn.2023.102433 · PMID:38065008 · W4389001091

review OA: closed CC0 ⤵ 9 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This systematic review and meta-analysis synthesized existing studies to evaluate the impact of high-intensity focused ultrasound (HIFU) treatment on reproductive outcomes in women with adenomyosis.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation High-Intensity Focused Ultrasound Ablation Female Female Female Female Female

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References (72)

A comparison of reproductive outcomes of patients with adenomyosis and infertility treated with High-Intensity focused ultrasound and laparoscopic excision via openalex
Adenomyosis and Infertility: A Literature Review via openalex
Adenomyosis: A reappraisal of symptomatology via openalex
Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease via openalex
Adverse effect analysis of high-intensity focused ultrasound in the treatment of benign uterine diseases via openalex
Anti-Müllerian hormone level may predict successful pregnancy after adenomyomectomy in patients with infertility due to adenomyosis via openalex
Changes in anti‐müllerian hormone levels as a biomarker for ovarian reserve after ultrasound‐guided high‐intensity focused ultrasound treatment of adenomyosis and uterine fibroid via openalex
Changing prostaglandin E2 (PGE<sub>2</sub>) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE<sub>2</sub> receptor EP2 and EP4 via openalex
Corroborating evidence for platelet-induced epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation in the development of adenomyosis via openalex
Current status of high-intensity focused ultrasound for the management of uterine adenomyosis via openalex
Endometriosis and infertility: a committee opinion via openalex
Fibrogenesis resulting from cyclic bleeding: the Holy Grail of the natural history of ectopic endometrium via openalex
Four subtypes of adenomyosis assessed by magnetic resonance imaging and their specification via openalex
Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling via openalex
High-intensity focused ultrasound (HIFU) combined with gonadotropin-releasing hormone analogs (GnRHa) and levonorgestrel-releasing intrauterine system (LNG-IUS) for adenomyosis: a case series with long-term follow up via openalex
High-intensity focused ultrasound (HIFU) for adenomyosis: Two-year follow-up results via openalex
Histological and Immunohistochemical Characterization of the Similarity and Difference Between Ovarian Endometriomas and Deep Infiltrating Endometriosis via openalex
Impact of adenomyosis on perinatal outcomes: a large cohort study (JSOG database) via openalex
Intrapartum uterine rupture following ultrasound‐guided high‐intensity focused ultrasound ablation of uterine fibroid and adenomyosis via openalex
Is High-intensity Focused Ultrasound Effective for the Treatment of Adenomyosis? A Systematic Review and Meta-analysis via openalex
Magnetic resonance guided high intensity focused ultrasound for uterine fibroids and adenomyosis has no effect on ovarian reserve via openalex
Magnetic Resonance Imaging-guided Focused Ultrasound Surgery in a Swine Adenomyosis Model via openalex
Pathophysiology of adenomyosis via openalex
Pregnancy and live birth after focused ultrasound surgery for symptomatic focal adenomyosis: a case report via openalex
Pregnancy outcome after high intensity focused ultrasound (HIFU) treatment for patients with adenomyosis via openalex
[Pregnancy outcomes and symptom improvement of patients with adenomyosis treated with high intensity focused ultrasound ablation]. via openalex
Safety of ultrasound-guided ultrasound ablation for uterine fibroids and adenomyosis: A review of 9988 cases via openalex
Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis via openalex
Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis via openalex
The Asian Society of Endometriosis and Adenomyosis guidelines for managing adenomyosis via openalex
The Effect of Uterine Adenomyosis on IVF Outcomes: a Systematic Review and Meta-analysis via openalex
The elusive adenomyosis of the uterus—revisited via openalex
The importance of the junctional zone of the endometrium in human reproduction via openalex
Ultrasound-guided percutaneous microwave ablation for adenomyosis: efficacy of treatment and effect on ovarian function via openalex
Ultrasound-guided transcervical radiofrequency ablation for symptomatic uterine adenomyosis via openalex
Uterine adenomyosis and adenomyoma: the surgical approach via openalex
Uterine rupture after high-intensity focused ultrasound ablation of adenomyosis: a case report and literature review via openalex
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Cited by (10)

Source provenance

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License: CC0 · commercial use OK

[1] A comparison of reproductive outcomes of patients with adenomyosis and infertility treated with High-Intensity focused ultrasound and laparoscopic excision via openalex

[2] Adenomyosis and Infertility: A Literature Review via openalex

[3] Adenomyosis: A reappraisal of symptomatology via openalex

[4] Adenomyosis in infertile women: prevalence and the role of 3D ultrasound as a marker of severity of the disease via openalex

[5] Adverse effect analysis of high-intensity focused ultrasound in the treatment of benign uterine diseases via openalex

[6] Anti-Müllerian hormone level may predict successful pregnancy after adenomyomectomy in patients with infertility due to adenomyosis via openalex

[7] Changes in anti‐müllerian hormone levels as a biomarker for ovarian reserve after ultrasound‐guided high‐intensity focused ultrasound treatment of adenomyosis and uterine fibroid via openalex

[8] Changing prostaglandin E2 (PGE<sub>2</sub>) signaling during lesional progression and exacerbation of endometriosis by inhibition of PGE<sub>2</sub> receptor EP2 and EP4 via openalex

[9] Corroborating evidence for platelet-induced epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation in the development of adenomyosis via openalex

[10] Current status of high-intensity focused ultrasound for the management of uterine adenomyosis via openalex

[11] Endometriosis and infertility: a committee opinion via openalex

[12] Fibrogenesis resulting from cyclic bleeding: the Holy Grail of the natural history of ectopic endometrium via openalex

[13] Four subtypes of adenomyosis assessed by magnetic resonance imaging and their specification via openalex

[14] Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling via openalex

[15] High-intensity focused ultrasound (HIFU) combined with gonadotropin-releasing hormone analogs (GnRHa) and levonorgestrel-releasing intrauterine system (LNG-IUS) for adenomyosis: a case series with long-term follow up via openalex

[16] High-intensity focused ultrasound (HIFU) for adenomyosis: Two-year follow-up results via openalex

[17] Histological and Immunohistochemical Characterization of the Similarity and Difference Between Ovarian Endometriomas and Deep Infiltrating Endometriosis via openalex

[18] Impact of adenomyosis on perinatal outcomes: a large cohort study (JSOG database) via openalex

[19] Intrapartum uterine rupture following ultrasound‐guided high‐intensity focused ultrasound ablation of uterine fibroid and adenomyosis via openalex

[20] Is High-intensity Focused Ultrasound Effective for the Treatment of Adenomyosis? A Systematic Review and Meta-analysis via openalex

[21] Magnetic resonance guided high intensity focused ultrasound for uterine fibroids and adenomyosis has no effect on ovarian reserve via openalex

[22] Magnetic Resonance Imaging-guided Focused Ultrasound Surgery in a Swine Adenomyosis Model via openalex

[23] Pathophysiology of adenomyosis via openalex

[24] Pregnancy and live birth after focused ultrasound surgery for symptomatic focal adenomyosis: a case report via openalex

[25] Pregnancy outcome after high intensity focused ultrasound (HIFU) treatment for patients with adenomyosis via openalex

[26] [Pregnancy outcomes and symptom improvement of patients with adenomyosis treated with high intensity focused ultrasound ablation]. via openalex

[27] Safety of ultrasound-guided ultrasound ablation for uterine fibroids and adenomyosis: A review of 9988 cases via openalex

[28] Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis via openalex

[29] Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis via openalex

[30] The Asian Society of Endometriosis and Adenomyosis guidelines for managing adenomyosis via openalex

[31] The Effect of Uterine Adenomyosis on IVF Outcomes: a Systematic Review and Meta-analysis via openalex

[32] The elusive adenomyosis of the uterus—revisited via openalex

[33] The importance of the junctional zone of the endometrium in human reproduction via openalex

[34] Ultrasound-guided percutaneous microwave ablation for adenomyosis: efficacy of treatment and effect on ovarian function via openalex

[35] Ultrasound-guided transcervical radiofrequency ablation for symptomatic uterine adenomyosis via openalex

[36] Uterine adenomyosis and adenomyoma: the surgical approach via openalex

[37] Uterine rupture after high-intensity focused ultrasound ablation of adenomyosis: a case report and literature review via openalex

[38] Who will benefit from uterus-sparing surgery in adenomyosis-associated subfertility? via openalex

[39] W2611026782 via openalex

[40] W1995954328 via openalex

[41] W1996860687 via openalex

[42] W2008760952 via openalex

[43] W2017044005 via openalex

[44] W2050166346 via openalex

[45] W2065067996 via openalex

[46] W2065685950 via openalex

[47] W2073962586 via openalex

[48] W2076711459 via openalex

[49] W2086680637 via openalex

[50] W2098923148 via openalex

[51] W2116475791 via openalex

[52] W2117452690 via openalex

[53] W2164111677 via openalex

[54] W2176164372 via openalex

[55] W2340612372 via openalex

[56] W2515052691 via openalex

[57] W2558364145 via openalex

[58] W2590059905 via openalex

[59] W315355381 via openalex

[60] W2753073405 via openalex

[61] W2805022447 via openalex

[62] W3035733632 via openalex

[63] W3119101527 via openalex

[64] W3122701507 via openalex

[65] W4385265654 via openalex

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[72] W6848648945 via openalex