Endometriosis-Related Complications in Women Undergoing In Vitro Fertilization

In: Endometriosis-related Infertility · 2024 · pp. 269–278 · doi:10.1007/978-3-031-50662-8_20 · W4392309707
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In vitro fertilization therapy may worsen endometriosis, potentially leading to complications like bowel blockage or abscesses, especially in women with pre-existing endometriosis.

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This chapter examines potential endometriosis-related complications in women undergoing in vitro fertilization (IVF), focusing on mechanisms such as IVF-associated elevated estrogen, altered ovulation frequency, and possible lesion inflammation, including in intestinal disease. It discusses associations between IVF procedures (including oocyte retrieval) and risks such as infection, pelvic inflammatory disease, and pelvic or tubo-ovarian abscess, noting that these problems may be more severe and persistent in women with endometriosis than in those without. A key caveat is that whether IVF accelerates endometriosis development is described as not yet ruled out or even proved, and the evidence base includes controversy. This paper is centrally about endometriosis — it specifically reviews endometriosis-related complications and potential disease progression concerns during IVF.

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Abstract

The potential danger of endometriosis worsening because of in vitro fertilization (IVF) therapy is a possible but underappreciated worry. As an estrogen-related disorder, the frequency of ovulation plays a key role in the development of ovarian endometriomas. The possibility that IVF accelerates the development of the illness has not yet been ruled out or even proved. Endometriotic lesions may become inflamed as a result of elevated estrogen levels associated with IVF, which is thought to cause serious consequences such as bowel blockage in individuals with intestinal lesions. The risk of infection, pelvic inflammatory disease, and pelvic or tubo-ovarian abscess have also been connected to IVF operations, including oocyte retrieval. When compared to women without endometriosis, these problems are often more severe and persistent in women with endometriosis. The possible endometriosis-related side effects and the controversies of IVF with endometrioma or endometriosis will be discussed in this chapter, along with advice on how to advise patients with high complications risk. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

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Risk factors for recurrence of deep infiltrating endometriosis after surgical treatment. J Obstet Gynaecol Res. 2021;47(8):2713–9. Author information Authors and Affiliations Editor information Editors and Affiliations Rights and permissions Copyright information © 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG About this chapter Cite this chapter Riemma, G., Vitale, S.G., Angioni, S. (2024). Endometriosis-Related Complications in Women Undergoing In Vitro Fertilization. In: Ferrero, S. (eds) Endometriosis-related Infertility. Springer, Cham. https://doi.org/10.1007/978-3-031-50662-8_20 Download citation DOI: https://doi.org/10.1007/978-3-031-50662-8_20 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-031-50661-1 Online ISBN: 978-3-031-50662-8 eBook Packages: MedicineMedicine (R0)

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