Treatment of unexplained infertility with danazol
RCT
OA: closed
CC0
⤵ 5 in-corpus citations
AI-generated summary
This randomized trial found that danazol treatment resulted in 3 full-term pregnancies in 21 women with unexplained infertility, compared to none in the 19 placebo recipients.
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Abstract
In order to investigate the possible stimulatory effect of danazol on fertility, a randomized clinical trial was performed on 40 women with unexplained infertility. Twenty-one women received 200 mg danazol daily for 100 days and 19 women received a placebo for the same period. No pregnancies occurred in the placebo group during a 6 month follow-up period. In the danazol group, 5 pregnancies occurred of which 1 were ectopic and 3 went to term.
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Cited by (5)
- Reduced expression of alphavbeta3 integrin in the endometrium of unexplained infertility patients with recurrent IVF-ET failures: improvement by danazol treatment 2003
- Is danazol a useful treatment in unexplained primary infertility? 1989
- The relationship of endometriosis to spontaneous abortion 1985
- Endometriosis 1984
- Changes of prolactin secretion following long-term danazol application 1981
Source provenance
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-10-08T21:46:40.609885+00:00
License: CC0
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