Influence of midluteal serum prolactin on outcome of pregnancy after IVF-ET: a preliminary study

Ozaki T, T Ozaki, Takahashi K, K. Takahashi, H Kurioka, Kurioka H, Miyazaki K, K. Miyazaki
Journal of assisted reproduction and genetics · 2001 · vol. 18(7) , pp. 387–90 · doi:10.1023/a:1016674523317 · PMID:11499323 · PMC3455825
Non-randomised trial OA: closed
📄 Open PDF View on PubMed View at publisher
⚙ AI-generated summary by qwen3.7-flash, 2026-08-29 ⓘ

This prospective study of 29 IVF-ET patients found that lower midluteal serum prolactin levels and higher progesterone-to-prolactin ratios were associated with early pregnancy loss, suggesting these markers may predict IVF outcomes.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

PURPOSE: To investigate the relationship between serum prolactin levels in the midluteal phase and the prognosis of pregnancy after IVF-ET. DESIGN: Prospective study; SETTING: Shimane Medical University Hospital; PATIENTS: 29 patients completing their 34th IVF cycle; and MAIN OUTCOME MEASURES: Serum levels of prolactin, estradiol-17 beta, and progesterone in the midluteal phase. RESULTS: Midluteal prolactin levels were significantly lower in patients with early pregnancy loss than in the successful pregnancy group. The mean progesterone/prolactin ratio and the estradiol-17 beta/prolactin ratio were highest in patients with early pregnancy loss and were lowest in patients with successful pregnancies. CONCLUSIONS: Findings of this study suggest that measurement of the serum prolactin concentration in the midluteal phase is useful for predicting the outcome of IVF-ET.

My notes (saved in your browser only)

MeSH descriptors

Embryo Transfer Fertilization in Vitro Infertility, Female Luteal Phase Prolactin Adult Estrogens Estrogens Female Gonadal Steroid Hormones Gonadal Steroid Hormones Humans Infertility, Female Luteal Phase Pregnancy Pregnancy Outcome Progesterone Progesterone Prognosis Prolactin

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
pubmed
last seen: 2026-10-08T20:59:59.992071+00:00
unpaywall
last seen: 2026-10-21T06:41:41.500114+00:00