Progranulin promotes proliferation, migration and invasion via the PI3K/Akt signalling pathway in a model of endometriosis
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This study investigates how progranulin enhances proliferation, migration, and invasion in an endometriosis model by activating the PI3K/Akt signaling pathway.
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References (28)
- Effects of inhibiting the PI3K/Akt/mTOR signaling pathway on the pain of sciatic endometriosis in a rat model via openalex
- Elevated phosphatase of regenerating liver 3 (PRL-3) promotes cytoskeleton reorganization, cell migration and invasion in endometrial stromal cells from endometrioma via openalex
- Endometriotic cell culture contamination and authenticity: a source of bias in <i>in vitro</i> research? via openalex
- Identification of an Invasive, N-Cadherin-Expressing Epithelial Cell Type in Endometriosis Using a New Cell Culture Model via openalex
- Imperatorin alleviated endometriosis by inhibiting the activation of PI3K/Akt/NF-κB pathway in rats via openalex
- p27kip1 overexpression regulates VEGF expression, cell proliferation and apoptosis in cell culture from eutopic endometrium of women with endometriosis via openalex
- Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review via openalex
- PI3K/AKT pathway is altered in the endometriosis patient’s endometrium and presents differences according to severity stage via openalex
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- The estrogen-regulated lncRNA H19/miR-216a-5p axis alters stromal cell invasion and migration via ACTA2 in endometriosis via openalex
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Cited by (5)
- Impaired decidualization and angiogenesis in eutopic endometrium of endometriosis: insights from in vitro models 2025
- Hua Yu Xiao Zheng decoction induces ectopic endometrial stromal cell senescence via inhibiting the PI3K/AKT signaling 2025
- The global burden of polycystic ovary syndrome, endometriosis, uterine fibroids, cervical cancer, uterine cancer, and ovarian cancer from 1990 to 2021 2025
- Research advances in endometriosis-related signaling pathways: A review 2023
- Tanshinone ⅡA participates in the treatment of endometriosis by regulating adhesion, invasion, angiogenesis and inhibition of PI3K/Akt/mTOR signaling pathway 2023
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-18T00:34:00.159478+00:00
- unpaywall
- last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0
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