Herlyn-Werner-Wunderlich syndrome: case reports

Kristina Jarienė
2025 · W7132180366
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This paper presents a case of Herlyn-Werner-Wunderlich syndrome in a 13-year-old girl, highlighting the importance of early diagnosis to prevent complications such as endometriosis.

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Herlyn-Werner-Wunderlich syndrome is a rare congenital Müllerian anomaly defined by the triad of uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. The paper describes this condition's typical presentation in adolescents as dysmenorrhea, pelvic pain, or a palpable mass resulting from hematocolpos or hematometra. It highlights that early diagnosis via imaging and surgical correction are essential to prevent complications such as endometriosis and infertility. This paper is centrally about endometriosis — specifically noting it as a potential complication of Herlyn-Werner-Wunderlich syndrome if left untreated.

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Abstract

Herlyn-Werner-Wunderlich (HWW) syndrome is a rare congenital Müllerian anomaly characterized by uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. It typically presents during adolescence with dysmenorrhea, pelvic pain, and, in some cases, a palpable pelvic mass due to hematocolpos or hematometra. Early diagnosis is crucial to prevent complications such as endometriosis and infertility. Imaging techniques, particularly MRI and ultrasound, play a key role in detection. Treatment involves surgical correction, usually through vaginal septum resection, to restore normal menstrual flow and alleviate symptoms. Multidisciplinary management is recommended for optimal patient outcomes. A clinical case of HWW syndrome in 13 year old girl will be presented
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Herlyn-Werner-Wunderlich syndrome: case reports | Author | |---| | Date | Start Page | End Page | |---|---|---| 2025-03-19 | 1 | 1 | Herlyn-Werner-Wunderlich (HWW) syndrome is a rare congenital Müllerian anomaly characterized by uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. It typically presents during adolescence with dysmenorrhea, pelvic pain, and, in some cases, a palpable pelvic mass due to hematocolpos or hematometra. Early diagnosis is crucial to prevent complications such as endometriosis and infertility. Imaging techniques, particularly MRI and ultrasound, play a key role in detection. Treatment involves surgical correction, usually through vaginal septum resection, to restore normal menstrual flow and alleviate symptoms. Multidisciplinary management is recommended for optimal patient outcomes. A clinical case of HWW syndrome in 13 year old girl will be presented.

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endometriosisdysmenorrheainfertility

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last seen: 2026-06-04T00:00:01.174412+00:00
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