Pancreaticoduodenectomy after downstaging of pancreatic carcinoma by chemotherapy

Hu JC, J C Hu, Bradman K, K Bradman, Taylor M, M Taylor, M Leslie, Leslie M, Parker MC, M C Parker
Journal of the Royal Society of Medicine · 2000 · vol. 93(8) , pp. 432–3 · doi:10.1177/014107680009300813 · PMID:10983509 · PMC1298089
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This study evaluates the feasibility and outcomes of performing pancreaticoduodenectomy in patients with locally advanced pancreatic carcinoma who have undergone downstaging via chemotherapy. The research focuses on determining whether preoperative systemic treatment can render unresectable tumors operable, thereby improving surgical resectability rates and potentially extending patient survival. While the text provided consists primarily of reference citations rather than a full abstract or results section, the title indicates an investigation into neoadjuvant strategies for pancreatic cancer management. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Full Text The Full Text of this article is available as a PDF (119.5 KB). Selected References These references are in PubMed. This may not be the complete list of references from this article. - Anderson K. E., Spitz I. M., Sassa S., Bardin C. W., Kappas A. Prevention of cyclical attacks of acute intermittent porphyria with a long-acting agonist of luteinizing hormone-releasing hormone. N Engl J Med. 1984 Sep 6;311(10):643–645. doi: 10.1056/NEJM198409063111006. [DOI] [PubMed] [Google Scholar] - Merk K., Björkholm M., Tullgren O., Mellstedt H., Holm G. Immune deficiency in family members of patients with Hodgkin's disease. Cancer. 1990 Nov 1;66(9):1938–1943. doi: 10.1002/1097-0142(19901101)66:93.0.co;2-o. [DOI] [PubMed] [Google Scholar] - Sparano J. A., Dutcher J. P., Kaleya R., Caliendo G., Fiorito J., Mitsudo S., Shechner R., Boley S. J., Gucalp R., Ciobanu N. Colonic ischemia complicating immunotherapy with interleukin-2 and interferon-alpha. Cancer. 1991 Oct 1;68(7):1538–1544. doi: 10.1002/1097-0142(19911001)68:73.0.co;2-2. [DOI] [PubMed] [Google Scholar]

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MeSH descriptors

Adenocarcinoma Pancreatic Neoplasms Adenocarcinoma Adenocarcinoma Chemotherapy, Adjuvant Female Humans Middle Aged Pancreatic Neoplasms Pancreatic Neoplasms Pancreaticoduodenectomy

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