Effect of an oral contraceptive on uterine tonicity in women with primary dysmenorrhea

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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study used hysterometry to measure uterine tonicity in dysmenorrheic women before and after oral contraceptive treatment, finding that the treatment decreased tonicity and relieved pain.

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Abstract

Hysterometry, a method for quantitative evaluation of the effect of pharmacologically active agents on the myometrium, has been applied to determine the effect of an oral contraceptive on uterine tonicity. Hysterometry was performed on the first day of each of two consecutive menstrual periods in 5 dysmenorrheic women. During the second cycle the women were given ethinylestradiol 50 microgram and lynestrenol 1 mg per day for 22 days. After the intake of this oral contraceptive, uterine tonicity decreased in all women, the decrease being accompanied by relief of dysmenorrheic pain.

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Condition tags

dysmenorrhea

MeSH descriptors

Contraceptives, Oral Contraceptives, Oral, Combined Dysmenorrhea Muscle Tonus Uterine Contraction Uterus Adolescent Adult Contraceptives, Oral Contraceptives, Oral, Combined Dysmenorrhea Dysmenorrhea Estradiol Estradiol Ethinyl Estradiol Ethinyl Estradiol Female Humans Lynestrenol Lynestrenol

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Cites (4)

Cited by (1)

References (19)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:58:42.677500+00:00
unpaywall
last seen: 2026-10-21T06:41:41.500114+00:00
License: CC0 · commercial use OK