Relaxin in endometriosis
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⤵ 3 in-corpus citations
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This study compared relaxin and its receptor mRNA expression in normal endometrium versus endometriosis samples to investigate relaxin's potential role in the disease.
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Abstract
Endometriosis is an important contributing factor to chronic pelvic pain and infertility. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) have each been implicated in the establishment of endometriotic lesions. Since relaxin regulates the expression of MMPs and VEGF in the endometrium, we tested the hypothesis that relaxin plays a role in endometriosis by comparing the expression of relaxin mRNA and its LGR7 (RXFP1) receptor mRNA in normal human endometrium to those in samples from patients with endometriosis.
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Too few in-corpus citations on either side for a chart; here are the lists.
Cites (4)
- Vascular endothelial growth factor A and C gene expression in endometriosis 2004
- The epidemiology of endometriosis 2010
- Matrix metalloproteinases and TACE play a role in the pathogenesis of endometriosis 2006
- Epidemiology of Endometriosis 2004
Cited by (3)
- The endometriotic tissue lining the internal surface of endometrioma: hormonal, genetic, epigenetic status, and gene expression profile 2014
- A new approach to the management of ovarian endometrioma to prevent tissue damage and recurrence 2016
- The Role of Relaxin in Normal and Abnormal Uterine Function During the Menstrual Cycle and Early Pregnancy 2016
References (6)
- Epidemiology of Endometriosis via openalex
- Matrix metalloproteinases and TACE play a role in the pathogenesis of endometriosis via openalex
- The epidemiology of endometriosis via openalex
- Vascular endothelial growth factor A and C gene expression in endometriosis via openalex
- W2145387518 via openalex
- W6715348775 via openalex
Cited by (3)
- The Role of Relaxin in Normal and Abnormal Uterine Function During the Menstrual Cycle and Early Pregnancy 2016
- A new approach to the management of ovarian endometrioma to prevent tissue damage and recurrence 2016
- The endometriotic tissue lining the internal surface of endometrioma: hormonal, genetic, epigenetic status, and gene expression profile 2014
Source provenance
- europepmc
- last seen: 2026-10-20T06:13:28.455750+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:06:23.467768+00:00
- unpaywall
- last seen: 2026-10-20T06:27:24.728081+00:00
License: CC0
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