Recurrent anaphylaxis to a depot form of GnRH analogue

G S Letterie, Letterie GS, D Stevenson, Stevenson D, A Shah, Shah A
Obstetrics and gynecology · 1991 · vol. 78(5 Pt 2) , pp. 943–6 · PMID:1923237
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This case report describes recurrent anaphylaxis to a depot GnRH analogue, highlighting the need for both acute and chronic management despite the rarity of such severe immediate hypersensitivity reactions.

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Abstract

Experience with depot forms of hormonal preparations suggests that severe adverse reactions are infrequent and immediate hypersensitivity reactions are rare. We report a case of recurrent anaphylaxis to a depot form of GnRH analogue requiring both acute and chronic management.

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Condition tags

endometriosis

MeSH descriptors

Anaphylaxis Leuprolide Adult Adult Anaphylaxis Anaphylaxis Anaphylaxis Anaphylaxis Delayed-Action Preparations Delayed-Action Preparations Emergencies Emergencies Endometriosis Endometriosis Endometriosis Female Female Humans Humans Leuprolide

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Source provenance

europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
pubmed
last seen: 2026-10-08T21:06:15.453410+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine