Endometrioma presenting as a cavitary lung mass with intense 18F-FDG uptake on PET-CT

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A 47-year-old woman was diagnosed with a pulmonary endometrioma presenting as a cavitary lung mass with intense 18F-FDG uptake on PET-CT, illustrating a benign false-positive result for malignancy.

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This case report describes a 47-year-old woman diagnosed with a pulmonary endometrioma that appeared as a cavitary lung mass exhibiting intense metabolic activity on positron emission tomography-computed tomography. The authors highlight that while fluorodeoxyglucose uptake typically suggests malignancy, benign lesions with high metabolic rates can produce false-positive results. This presentation underscores the diagnostic challenge of distinguishing between malignant processes and rare benign conditions based solely on imaging characteristics. This paper is centrally about endometriosis — specifically an unusual extrapelvic manifestation known as thoracic endometriosis presenting in the lungs.

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Abstract

[18F]-fluoro-2-deoxy-D-glucose positron emission tomography computed tomography is a useful tool to suggest the diagnosis of malignant processes. However, false positive results are known to occur in benign lesions that have a high metabolic activity. Here we describe the unusual diagnosis of a pulmonary endometrioma in a 47-year-old woman, presenting as a cavitary lung mass with intense (18)F-FDG uptake on PET-CT.
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Case Reports—Pulmonary Endometrioma Presenting as a Cavitary Lung Mass With Intense 18 F-FDG Uptake on PET-CT - Anna Y. Derman - Dan Sperling - Avraham Merav - Vineet R. Jain - Miles Levin - Suman Jana - Linda B. Haramati [18F]-fluoro-2-deoxy-D-glucose positron emission tomography computed tomography is a useful tool to suggest the diagnosis of malignant processes. However, false positive results are known to occur in benign lesions that have a high metabolic activity. Here we describe the unusual diagnosis of a pulmonary endometrioma in a 47-year-old woman, presenting as a cavitary lung mass with intense 18F-FDG uptake on PET-CT. Copyright © 2007 Lippincott Williams & Wilkins, Inc.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Fluorodeoxyglucose F18 Fluorodeoxyglucose F18 Lung Neoplasms Positron-Emission Tomography Radiopharmaceuticals Radiopharmaceuticals Tomography, X-Ray Computed Cough Cough Cough Diagnosis, Differential Diagnosis, Differential Endometriosis Endometriosis Endometriosis Female Female Hemoptysis Hemoptysis

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europepmc
last seen: 2026-11-01T09:25:17.647243+00:00
pubmed
last seen: 2026-10-08T21:04:24.806248+00:00
unpaywall
last seen: 2026-11-02T06:26:32.194460+00:00
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