[French clinical practice guidelines developed by a modified Delphi consensus process for oocyte vitrification in women with benign gynecologic disease]

B Courbiere, Blandine Courbière, Le Roux E, E. Le roux, Mathieu d'Argent E, Emmanuelle Mathieu d’Argent, E Mathieu d'Argent, A Torre, Torre A, Antoine Torre, Patrat C, Catherine Patrat, C Patrat, Poncelet C, C. Poncelet, J. Montagut, Montagut J, A.-S. Grémeau, Gremeau AS, A.-S. Gremeau, Creux H, H. Creux, M Peigne, Peigne M, Maëliss Peigné, Isabella Chanavaz‐Lacheray, I Chanavaz-Lacheray, Chanavaz-Lacheray I, L Dirian, Dirian L, Lara Dirian, X Fritel, Xavier Fritel, Pouly JL, J.-L. Pouly, Fauconnier A, Arnaud Fauconnier, A Fauconnier
Gynecologie, obstetrique, fertilite & senologie · 2022 · vol. 50(3) , pp. 211–219 · doi:10.1016/j.gofs.2022.01.003 · PMID:35063688 · W4206453386
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This Delphi consensus study established 28 practice guidelines for fertility preservation via oocyte vitrification in women with benign gynecological diseases.

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Abstract

OBJECTIVES: To provide clinical practice guidelines about fertility preservation (FP) for women with benign gynecologic disease (BGD) developed by a modified Delphi consensus process for oocyte vitrification in women with benign gynecologic disease. METHODS: A steering committee composed of 14 healthcare professionals and a patient representative with lived experience of endometriosis identified 42 potential practices related to FP for BGD. Then 114 key stakeholders including various healthcare professionals (n=108) and patient representatives (n=6) were asked to participate in a modified Delphi process via two online survey rounds from February to September 2020 and a final meeting. Due to the COVID-19 pandemic, this final meeting to reach consensus was held as a videoconference in November 2020. RESULTS: Survey response of stakeholders was 75 % (86/114) for round 1 and 87 % (75/86) for round 2. Consensus was reached for the recommendations for 28 items, that have been distributed into five general categories: (i) Information to provide to women of reproductive age with a BGD, (ii) Technical aspects of FP for BGD, (iii) Indications for FP in endometriosis, (iv) Indications for FP for non-endometriosis BGD, (v) Indications for FP after a fortuitous diagnosis of an idiopathic diminished ovarian reserve. CONCLUSION: These guidelines provide some practice advice to help health professionals better inform women about the possibilities of cryopreserving their oocytes prior to the management of a BGD that may affect their ovarian reserve and fertility. STUDY FUNDING/COMPETING INTEREST(S): The CNGOF (Collège National des Gynécologues Obstétriciens Français) funded the implementation of the Delphi process.

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endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Consensus Consensus Delphi Technique Delphi Technique Female Female Humans Humans Oocytes Oocytes Oocytes Vitrification Vitrification

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