European journal of drug metabolism and pharmacokinetics
Eur J Drug Metab Pharmacokinet
· ISSN (e) 2107-0180
· 2 papers in corpus
nonrandomized-trial
BACKGROUND: Overactive adenosine triphosphate signaling via P2X3 homotrimeric receptors is implicated in multiple conditions. To fully understand the metabolism and elimination pathways of eliapixant, a study was conducted to assess the pha…
lab-animal
2018
BACKGROUND AND OBJECTIVES: Previous studies have demonstrated the metabolism of tibolone through sulfation, with the cytosolic sulfotransferase (SULT) SULT2A1 as the major responsible enzyme. The current study aimed to investigate how SULT2…