The use of the various new progestins in the treatment of endometrio sis is reported. Data from at least 6 separate investigators indicate an improvement rate of between 75% and 85%. In 1958 Kistner reported results in 12 patients using com…
Studies were carried out on the effects of administration of Lyndiol on circulation and blood coagulation. Various clinical observations are presented. In Week 1 of Lyndiol medication there was a regulation of the blood stream closely resem…
The efficacy of therapeutic doses of Provest (10 mg medroxyprogesterone acetate .05 mg ethinyl estradiol) in controlling adolescent menstrual disorders was evaluated in 19 girls. Treatment for 3-6 months satisfactorily prevented amenorrhea-…
OBJECTIVE: To compare efficacy of various methods for characterizing endometriosis and benign ovarian tumors. DESIGN: Two parallel groups of patients, 54 with endometriotic ovarian cysts and 48 with benign tumors. SETTING: Central clinic.…
CA 125 levels were measured in the serum of 18 patients with laparoscopically diagnosed stage 2 to stage 4 endometriosis (American Fertility Society classification) and in eight normally cycling control women. All endometriosis patients wer…
Coagulation factor activity was evaluated in female rats treated with danazol. Following 30 days of treatment, slight decreases in factor VII and X activities were noted. After 60 days, a prolongation of the prothrombin time, as well as a d…
Glycogen content in endometrium with endometriosis was about half of that without endometriosis at the secretory phase, whereas no difference was found in the proliferative phase. The activity of glycogen synthetase in endometrium with endo…
Apparently conflicting results have been reported regarding the incidence, and even the existence, of endometriosis in visually normal peritoneum. The present study was undertaken in view of the fact that the presence and incidence of nonvi…
A retrospective study was designed to compare the results of treatment of moderate and severe stages of endometriosis by laparotomy and by laparoscopy. Patients were divided into three groups: the first consisted of 42 patients treated by l…
In order to assess adequately the effectiveness of danazol, Gestrinone, and Buserelin, a prospective nonrandomized study was initiated in 126 patients with laparoscopically confirmed ovarian endometriosis. After hormonal therapy, laparotomy…
Intrauterine insemination is commonly performed in the treatment of infertility. Infectious complications associated with intrauterine insemination are frequently cited, though rarely reported. A review of the literature yields only five re…
Intraperitoneal superoxide dismutase (SOD) and catalase were used to block the toxic effects of superoxide anion (O2) and hydrogen peroxide (H2O2), associated with the production of endometriosis and inflammation in a rabbit model. In a two…
The benefits of oral contraceptives are emphasized in this review which begins by listing the priorities an older career woman seeks in a contraceptive. She needs a highly reliable reversible method while she postpones childbearing until as…
Additional details of a multicenter study of nafarelin acetate with particular attention to a unique endometriosis scoring system utilized are reviewed. Additional information regarding the relapse of symptoms of 10 patients treated with na…
Serum levels of CA 125 in 33 patients with progressive external endometriosis who were treated with 400 mg/day of Danazol for 16 weeks were assayed for an extended period (24-40 weeks), and changes in the CA 125 pattern were analyzed. Patte…
The present report examines retrospectively the success rates of both in-vitro fertilization and embryo transfer (IVF-ET) and gamete intrafallopian transfer (GIFT) in relation to the underlying infertility disorder. Reduced fertilization ra…
A pelvic scoring system for infertility surgery was devised in which pelvic pathology is assessed for comparative and prognostic purposes. Pelvic pathology was divided into three areas: adhesions (ADH), salpingitis (SPG), and tubal occlusio…
Twenty-one patients undergoing laparoscopy and chromotubation were investigated for the dissemination of endometrial cells into the pelvic cavity. Prechromotubation fluid and postchromotubation fluid from the posterior cul-de-sac were aspir…
The present case report illustrates the hormonal sensitivity of adenomyosis. Administration of an estrogen-progestin combination for what was felt to be symptomatic endometriosis resulted in exacerbation of symptoms and growth of adenomyoma…
The ovarian function of 11 patients suffering from estrogen-dependent disorders and ovarian dysfunction was suppressed by monthly administrations of an analogue of luteinizing hormone-releasing hormone (LH-RH). During the initial 11 to 18 d…
The success of IVF has established it as a viable alternative to microsurgery in the treatment of infertility associated with certain types of tubal occlusion. The authors have recently reported on the success rates of microsurgery versus I…