Frontiers in bioinformatics

INTRODUCTION: Ovarian cancer is one of the most lethal gynecological malignancies, largely due to its asymptomatic onset, heterogeneous molecular landscape, and frequent late-stage diagnosis. Identifying key oncogenic drivers and novel ther…

Understanding the molecular effects associated with glyphosate exposure remains challenging due to the fragmentation of available evidence across heterogeneous data sources. This study aimed to integrate heterogeneous molecular evidence rel…

ObjectiveCSF2RB is the common beta chain of the heterodimeric receptors for the cytokines, granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin 3 (IL-3), and interleukin 5 (IL-5). The activation of these cell surface recep…

INTRODUCTION: The Re1-Silencing Transcription Factor (REST) is a master regulator of gene silencing, orchestrating transcriptional repression by tethering chromatin-modifying co-repressors to the Re1 motif of target genes. While REST is rec…