European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Eur J Pharm Biopharm · ISSN (e) 1873-3441 · 7 papers in corpus
lab-animal 2026
doi:10.1016/j.ejpb.2026.115237 ·PMID:42778111

Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by ectopic endometrial-like glands and stroma, persistent pelvic inflammation, pain, infertility, and frequent recurrence. The limited availability of nonhorm…

lab-animal 2026
doi:10.1016/j.ejpb.2026.115022 ·PMID:41690332

Elagolix sodium (ELS), a non-peptide oral gonadotropin-releasing hormone receptor (GnRH) antagonist approved for the treatment of endometriosis-associated pain, displays atypical gelation in aqueous environments along with challenging physi…

review 2021
doi:10.1016/j.ejpb.2020.12.005 ·PMID:33338604

In the field of drug delivery, the most commonly used treatments have traditionally been systemically delivered using oral or intravenous administration. The problems associated with this type of delivery is that the drug concentration is c…

other 2019
doi:10.1016/j.ejpb.2019.05.024 ·PMID:31150808

Oral bioavailability of poorly water soluble (BCS II) drugs like danazol can be minimal without the necessary formulation strategies. Availability of in vitro physicochemical and in vivo pharmacokinetic studies can be valuable when designin…

lab-animal 2019
doi:10.1016/j.ejpb.2019.09.023 ·PMID:31563633

Nanoscale cerium dioxide (nanoceria) has industrial applications, capitalizing on its catalytic, abrasive, and energy storage properties. It auto-catalytically cycles between Ce3+ and Ce4+, giving it pro-and anti-oxidative properties. The l…

lab-animal 2016
doi:10.1016/j.ejpb.2016.01.007 ·PMID:26776271

Cyclodextrins (CDs) are frequently used as an excipient to enhance the intestinal drug absorption of compounds with a low aqueous solubility. However, there exists an intricate interplay between opposing effects that determine the optimal d…

lab-animal 2011
doi:10.1016/j.ejpb.2011.02.007 ·PMID:21329757

The usefulness of selected conventional surfactant media to enhance dissolution of BCS class II drugs similarly to fasted state simulated intestinal fluid (FaSSIF) and to predict the absorption of drugs in vivo was evaluated. Dissolution be…