Clinics (Sao Paulo, Brazil)

Clinics (Sao Paulo) · ISSN (e) 1980-5322 · 18 papers in corpus · 2008-2026

Year distribution

Study types

  • article 10
  • other 6
  • editorial 1
  • review 1

Condition tags

  • endometriosis 17
  • mesh:D004715 15
  • dysmenorrhea 5
  • infertility 5
  • dyspareunia 4
  • adenomyosis 2
  • endometrioma 2
  • mesh:D004412 2
  • die_deep_infiltrating 1
  • mesh:D004414 1
other 2026
doi:10.1016/j.clinsp.2026.100895 ·PMID:41780295

OBJECTIVE: Chronic Pelvic Pain (CPP) presents significant diagnostic challenges, often involving multiple pathologies, including endometriosis and pelvic venous disorders. This study examined the prevalence of endometriosis among women with…

article 2025
doi:10.1016/j.clinsp.2025.100760 ·PMID:40915181

BACKGROUND: Endometriosis diagnosis is challenging due to non-specific symptoms that overlap with other gynaecological conditions. This study proposes a non-invasive Machine Learning (ML) ‒ based urine test using Attenuated Total Reflection…

article 2025
doi:10.1016/j.clinsp.2025.100700 ·PMID:40517681

OBJECTIVE: To investigate the incidence of postoperative venous thromboembolism in women with uterine adenomyosis treated using different surgical methods, and to evaluate the associated clinical and laboratory parameters, including thrombo…

review 2025
doi:10.1016/j.clinsp.2025.100654 ·PMID:40273491

• ω−3 PUFAs had no significant effect on endometriosis symptoms, such as pain, etc. • ω−3 PUFAs could reduce the inflammatory response in patients with endometriosis. • The local environment of implants exhibits pre-inflammatory tissue char…

article 2024
doi:10.1016/j.clinsp.2023.100317 ·PMID:38432123

OBJECTIVE: To evaluate the relationship between genetic haplotypes associated with celiac disease (Human Leucocyte Antigen [HLA] DQ2 and DQ8) with the diagnosis, clinical presentation, and location of endometriosis in Brazilian women. METHO…

article 2024
doi:10.1016/j.clinsp.2024.100390 ·PMID:38781760

Endometriosis's pathophysiology remains incompletely understood, with evidence pointing towards a dysregulated immune response. Regulatory T (Treg) cells, pivotal in maintaining self-tolerance, may facilitate the survival of ectopic endomet…

editorial 2024
doi:10.1016/j.clinsp.2024.100326 ·PMID:38325019

It is time to change the definition: Endometriosis is no longer a pelvic disease Endometriosis is a chronic, inflammatory, hormone-dependent gynecologic condition characterized by the presence of endometrial-like tissue outside the uterine …

other 2023
doi:10.1016/j.clinsp.2023.100176 ·PMID:36893562
other 2023
doi:10.1016/j.clinsp.2023.100224 ·PMID:37331213

BACKGROUND: Endometriosis is a chronic inflammatory disease affecting about 10% of women of reproductive age. Endometrioma is the most common presentation of endometriosis in ovaries. OBJECTIVES: Herein, the authors study the effect of the…

article 2023
doi:10.1016/j.clinsp.2023.100235 ·PMID:37392565

Recent studies have found that lncRNA-MEG3(MEG3) plays an important role in the development of EMs (Endometriosis), but the specific mechanism needs to be further explored. This study aimed to investigate the effect of MEG3 on the prolifera…

other 2022
doi:10.1016/j.clinsp.2022.100074 ·PMID:35793608

OBJECTIVE: To evaluate the expression of Ezrin and Phosphorylated Ezrin (Phospho-Ezrin) in endometriosis lesions and its relation to the menstrual cycle phase, stage of endometriosis, histological classification, and clinical symptoms. MAT…

article 2022
doi:10.1016/j.clinsp.2022.100032

To evaluate the frequencies of iNKT cells and their subsets in patients with deep endometriosis. A case-control study was conducted between 2013 and 2015, with 73 patients distributed into two groups: 47 women with a histological diagnosis …

other 2022
doi:10.1016/j.clinsp.2022.100112 ·PMID:36244127

OBJECTIVE: This study was designed to evaluate the expression of microRNA-223 (miRNA-223) in patient-derived eutopic and ectopic endometrial stromal cells (SCs). Given the fact that miRNA-223 was previously shown to be upregulated in these …

other 2021
doi:10.6061/clinics/2021/e2981 ·PMID:34406269

OBJECTIVE: To evaluate the association of two-dimensional (2D) and three-dimensional (3D) transvaginal ultrasound (TVUS) findings with adenomyosis symptoms. METHODS: This prospective study conducted between January and December 2018 enroll…

article 2019
doi:10.6061/clinics/2019/e989 ·PMID:31291391

OBJECTIVE: Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and coupling an LDL-like nanoemulsion, containing lipid nanoparticles (LDE) to…

article 2012
doi:10.6061/clinics/2012(05)06 ·PMID:22666786

OBJECTIVE: Differentiation between benign and malignant ovarian neoplasms is essential for creating a system for patient referrals. Therefore, the contributions of the tumor markers CA125 and human epididymis protein 4 (HE4) as well as the …

article 2010
doi:10.1590/s1807-59322010001100002 ·PMID:21243274

OBJECTIVE: This study aimed to determine the frequency of the PROGINS polymorphism in women with endometriosis-associated infertility, in infertile women without endometriosis and in controls. INTRODUCTION: The human progesterone receptor g…

article 2008
doi:10.1590/s1807-59322008000400019 ·PMID:18719766

OBJECTIVE: To evaluate the effects of estrogen treatment in combination with gestrinone on an experimental rat model of endometriosis. METHODS: Uterine transplants were attached to the peritoneum of female Wistar rats via a surgical autotra…