Journal of pharmaceutical and biomedical analysis

J Pharm Biomed Anal · ISSN (e) 1873-264X · 12 papers in corpus
other 2025
doi:10.1016/j.jpba.2025.116708 ·PMID:39879821

Isothermal, enzyme-free amplification techniques, such as the hybridization chain reaction (HCR) and catalytic hairpin assembly (CHA), have gained significant attention for mRNA analysis. Despite their potential, these methods still face ch…

lab-animal 2024
doi:10.1016/j.jpba.2024.115970 ·PMID:38277707

BACKGROUND: Endometriosis is a gynecological disease that causes severe chronic pelvic pain and infertility in women. The therapeutic efficacy of the traditional herbal combination of Sparganium stoloniferum-Curcuma phaeocaulis (Sangleng-Ez…

lab-animal 2023
doi:10.1016/j.jpba.2022.115198 ·PMID:36495708

Elagolix sodium (ELS) is a marketed product using to release moderate to severe endometriosis-associated pain. It contains functional groups such as carboxyl group, secondary amino group, 2,4-dioxo pyrimidinyl and several benzyl or benzyl-l…

other 2019
doi:10.1016/j.jpba.2019.07.004 ·PMID:31387028

In the context of hormonal contraception and hormone replacement therapy (HRT), many women are exposed to exogenous hormones. Current use of hormonal contraception with combined ethinyl estradiol and different progestins bestows a breast ca…

observational 2019
doi:10.1016/j.jpba.2019.04.048 ·PMID:31063881

Endocrine disrupting chemicals (EDCs) such as phthalates and bisphenol A (BPA) are substances that may interfere with the actions of endogenous hormones and may be associated with estrogen-related diseases such as endometriosis. This paper …

other 2018
doi:10.1016/j.jpba.2018.01.034 ·PMID:29414008

An LC-MS/MS method was developed and validated to analyze simultaneously estrogens (estradiol, E2; estrone, E1), androgens (testosterone, T; androstenedione, A4; dehydroepiandrosterone, DHEA), progestagens (17a-hydroxypregnenolone, 17OHP5; …

other 2006
doi:10.1016/j.jpba.2005.11.046 ·PMID:16510262

Based on the interfacial adsorptive character of danazol onto the hanging mercury drop electrode (HMDE), a simple and sensitive square-wave adsorptive stripping voltammetric (SW-AdSV) procedure for the electrochemical analysis of this drug …

other 2004
doi:10.1016/j.jpba.2004.10.011 ·PMID:15664763

The voltammetric behaviour of danazol DZ (antigonadotropin) was studied using cyclic voltammetry, direct current, differential pulse polarography (DPP) and alternating current polarography. Danazol exhibited irreversible cathodic waves over…

other 2003
doi:10.1016/s0731-7085(03)00224-3 ·PMID:14565547

Two isocratic liquid chromatographic methods (conventional and micellar) for the determination of danazol (DZ) in capsules using canrenone (CAN) as internal standard have been developed and validated. In conventional liquid chromatography a…

other 2000
doi:10.1016/s0731-7085(00)00315-0 ·PMID:10933534

A selective high-performance liquid chromatographic procedure for the stability-indicating determination of danazol in the presence of its photolytic degradation products is demonstrated. The photolysis was carried out in glass vials and qu…

review 1993
doi:10.1016/0731-7085(93)80107-c ·PMID:8123737

Impurities in drugs are classified on the basis of the types of side-reactions in drug syntheses resulting in their formation. This is shown by summarizing the authors' earlier results in the field of impurity profiling of 19-nor-steroids, …

other 1990
doi:10.1016/0731-7085(90)80010-m ·PMID:2131807

A liquid chromatographic method for the determination of danazol in human serum has been developed. Reversed-phase C8 and C18 columns were used with a column-switching valve, isocratic elution and UV detection. Sample pretreatment involved …