Nihon Sanka Fujinka Gakkai zasshi

Thirty-six patients with ovarian endometriosis were treated with Nd:YAG laser contact irradiation under laparoscopic control. Indications for laparoscopy were infertility (n = 20) and dysmenorrhea (n = 16). The laparoscopic procedures so fa…

The SHIN-3 cell line producing CA125 was established from an ovarian cancer patient. Using the SHIN-3 cell line, we found that the low-molecular-mass antigen (about 50 KDa) might be the main antigenic determinant in CA125-immunoreactive spe…

Human eutopic and heterotopic endometrium were cultured and epithelial cells were isolated from stromal cells by the modified method of Satyaswaroop et al. in order to investigate the cause of elevated serum CA125 levels in patients with ad…

Immunohistochemical study with various monoclonal antibodies to the mononuclear cell surface antigens was carried out on the regional lymph nodes in patients with cervical cancer to assess the augmentative effect of lentinan. Zero, 2, 4, or…

By means of transvaginal ultrasonography, endometrial activity was investigated in its relationship with uterine contraction and ovarian hormones. The following results were obtained. (1) Endometrial movements were classified into two types…

We investigated the value of MRI in investigating uterine anatomy and disease. 1. Normal uterus: The signal intensity and endometrial thickness changed during the menstrual cycle. Endometrial thickness in the secretory phase was 12.8 +/- 3.…

We investigated the usefulness of measuring the serum CA19-9 concentration in the diagnosis and therapeutic monitoring of endometriosis, and compared it with the serum CA125 concentration. We added an immunohistochemical study on CA19-9 and…

Clinically we rather frequently treat infertile women with endometriosis, either external or internal. Nowadays the study of the histogenesis of endometriosis is urgently required by patients who suffer from sterility because of endometriot…

Danazol, which is commonly employed in the treatment of endometriosis creates a low estrogen and high androgen condition by suppressing ovarian steroidogenesis. When a reproductive-aged woman suddenly develops low estrogen, even if it is re…

Sixty-two patients with gynecological disease, who were treated with sizofiran (SPG) intramuscularly before laparotomy or with recombinant interferon gamma (IFN) intraperitoneally on the day of the laparotomy, were studied to investigate th…

In the present study 18 cases of malignant ovarian neoplasm were studied to determine the possible role of sex steroid hormones and gonadotropins on tumor development. Twelve cases of serous cystadenocarcinoma, 2 of mucinous cystadenocarcin…

To clarify the mechanism of infertility associated with endometriosis (EM), the effect of peritoneal fluid (PF) on early embryogenesis was examined. The addition of PF (5%) had no effect on the development of mouse 2-cell embryos. Since the…

An outpatient department screening method for endometriosis was prepared by designing a scoring system in a retrospective study. We compared the incidence of 21 characteristic symptoms and the finding of endometriosis in 39 infertile women …

The clinical features and the intrafollicular environment of luteinized unruptured follicle (LUF) were investigated in 60 infertile women by means of ultrasonography. LUF was diagnosed in daily ultrasound scans in 52 (13.5%) of 384 apparent…

Normal human endometrial epithelial cells were obtained from premenopausal women at the time of necessary hysterectomy. The cells were cultured in, or on, collagen gels in a serum-free medium, and were also co-cultured with endometrial stro…

The possibility of the endometrial production of CA125 and the effect of P4, MPA, and E2 were investigated using tissue cultures of eutopic endometrium (uterine endometrium obtained from uterine myoma) and heterotopic endometrium (uterine m…

A serological diagnosis of ovarian carcinoma was performed using a combination assay consisting of three tumor markers. Cancer Antigen 125 (CA125), Sialyl Lex-i (SLX), and CA72-4. The results were compared with those for the individual tumo…

The clinical and pathological findings in 23 cases of clear cell carcinoma of the ovary treated at Cancer Institute Hospital from January 1951 to September 1987 are discussed. Clear cell carcinoma accounted for 7.1% of all malignant tumors …

This study was designed to compare the clinical and hormonal efficacy of the treatment for endometriosis using continuous infusion of three different doses of GnRH agonist (A). In addition, we examined the ovarian responsiveness to human me…