Irene Souter

BACKGROUND/OBJECTIVES: The aim of this study was to investigate the association between antioxidant intake and antral follicle count (AFC), a marker of ovarian reserve, in women attending a fertility clinic. METHODS: We conducted an observ…

BACKGROUND/OBJECTIVES: Few studies have investigated the association of dietary glycemic index (GI), glycemic load (GL), and carbohydrate intake with antral follicle count (AFC). This study aimed to investigate the association of total carb…

BACKGROUND: Phenols are a family of short-lived endocrine disrupting chemicals found in a wide range of products and have drawn significant attention because of widespread human exposure and their potential adverse effects on reproductive h…

Exposure to phthalates is common and difficult to avoid. However, intake of long-chain n-3 polyunsaturated fatty acids (n3PUFAs) may ameliorate negative effects on ovarian reserve by exposure to phthalates as both are involved in key proces…

PURPOSE: To evaluate the association, if any, between the grade of the trophectoderm (TE) and the rate at which β-human-chorionic gonadotropin (β-HCG) rises in early pregnancy. METHODS: This is a retrospective cohort study including 1116 s…

OBJECTIVE: To investigate the association between intake of soy food and isoflavone with ovarian reserve. Previous studies suggest on the relationship between soy intake and human fertility are inconsistent. Some clinical studies suggest th…

OBJECTIVE: To report a case of ovarian torsion during ovarian stimulation prior to trigger followed by laparoscopic detorsion, trigger, and subsequent successful oocyte retrieval, as well as to review outcomes from the cycle. CASE PRESENTA…

PURPOSE: To study the association, if any, between anti-Müllerian hormone (AMH) and pre-ovulatory endometrial thickness (ET) in gonadotropin/intrauterine insemination (IUI) cycles. METHODS: This retrospective cohort study included a total …

PURPOSE: To determine if creating voting ensembles combining convolutional neural networks (CNN), support vector machine (SVM), and multi-layer neural networks (NN) alongside clinical parameters improves the accuracy of artificial intellige…

OBJECTIVE: To evaluate the associations of caffeinated, alcoholic, and sweetened beverage intakes with antral follicle count (AFC), a well-accepted biomarker of ovarian reserve. DESIGN: Observational prospective cohort study. SETTING: Fer…

OBJECTIVE: To compare the variability in metabolomes between the serum and follicular fluid, as well as across 3 dominant follicles. DESIGN: Prospective cohort study. SETTING: An academic fertility clinic in the northeastern United States…

OBJECTIVE: To examine the association between ambient temperature and antral follicle count (AFC), a standard measure of ovarian reserve. DESIGN: Prospective cohort study. SETTING: Fertility center at an academic hospital in the northeast…

PURPOSE(S): To evaluate the relationship of men's dietary patterns with outcomes of in vitro fertilization (IVF). METHODS: This is a prospective cohort study including 231 couples with 407 IVF cycles, presented at an academic fertility cen…

BACKGROUND: Few epidemiologic studies have evaluated the impact of paternal environmental exposures, particularly as mixtures, on couples' pregnancy outcomes. OBJECTIVE: We investigated whether mixtures of paternal urinary bisphenol A (BPA…

BACKGROUND: Overweight and obesity among women have been associated with lower success of assisted reproduction technologies (ARTs). However, the relation of adolescent body weight and adult weight change to ART outcomes is not well underst…

PURPOSE: We aimed to assess whether home collection and increased time to semen processing are associated with altered sperm parameters, fertilization rates (FR), day 5 usable quality blastocyst development rates (D5-UQBR), or pregnancy rat…

Exposure to phthalates, endocrine-disrupting chemicals commonly used as plasticizers and in consumer products, has been associated with infertility and premature ovarian failure. Our objective was to investigate whether urinary phthalate me…

Accumulating evidence suggests that air pollution increases pregnancy loss; however, most previous studies have focused on case identification from medical records, which may underrepresent early pregnancy losses. Our objective was to inves…

OBJECTIVE: To investigate the associations between dietary patterns and antral follicle count (AFC), a marker of ovarian reserve. DESIGN: Prospective cohort study. SETTING: Fertility center at an academic hospital. PATIENT(S): A total of…

BACKGROUND: An increasing number of studies have linked air pollution to decreased fertility. Whether this is due to an effect on ovarian reserve is unknown. METHOD: Our study included 632 women attending the Massachusetts General Hospital…

BACKGROUND: Randomized trials of supplementation with antioxidant mixtures during infertility treatment show no benefit on pregnancy or live birth rate. However, the roles of individual antioxidants are poorly understood. We examined the as…

RESEARCH QUESTION: Studies in rodents have shown that paternal folate intake prior to conception is associated with pregnancy and offspring outcomes. The aim of this study was to assess whether those associations might apply to humans as we…

IMPORTANCE: Animal experiments suggest that ingestion of pesticide mixtures at environmentally relevant concentrations decreases the number of live-born offspring. Whether the same is true in humans is unknown. OBJECTIVE: To examine the as…

OBJECTIVE: To evaluate the relationship between demographic, lifestyle, and reproductive factors and the risk of ectopic pregnancy (EP). DESIGN: Prospective cohort. SETTING: United States. PATIENT(S): Nurses' Health Study II cohort compr…