Walter Jäger

No ORCID on file · 2 papers in corpus

lab-animal 2021

Altered Profile of E1-S Transporters in Endometrial Cancer: Lower Protein Levels of ABCG2 and OSTβ and Up-Regulation of SLCO1B3 Expression

International journal of molecular sciences ·doi:10.3390/ijms22083819

Endometrial cancer (EC) is associated with increased estrogen actions. Locally, estrogens can be formed from estrone-sulphate (E1-S) after cellular uptake by organic anion-transporting polypeptides (OATP) or organic anion transporters (OAT)…

review 2013

The sulfatase pathway for estrogen formation: targets for the treatment and diagnosis of hormone-associated tumors

Journal of drug delivery ·doi:10.1155/2013/957605

The extragonadal synthesis of biological active steroid hormones from their inactive precursors in target tissues is named "intracrinology." Of particular importance for the progression of estrogen-dependent cancers is the in situ formation…