Chunwei Cao
ORCID: 0000-0001-8114-7589
· 9 papers in corpus
lab-animal
2026
Iron overload induces cellular stress and is implicated in diverse pathological conditions. Nevertheless, the epigenetic mechanisms governing mammalian cellular responses to iron overload remain poorly characterized. Using multi-omics profi…
lab-animal
2026
Unexplained recurrent pregnancy loss (URPL) represents a prevalent obstetric complication and remains a challenging condition with poorly understood genetic etiology. Through whole-exome sequencing of 94 URPL patients, we identified enriche…
other
2026
In brief: We present the first single-cell transcriptomic atlas of follicular fluid from an ovarian endometrioma (OMA) patient, revealing a novel TCR+ macrophage subtype, aberrant granulosa cell developmental trajectories, immune dysregulat…
lab-animal
2025
Ovarian endometrioma (OMA), an estrogen-dependent gynecological disorder, is characterized by the presence of abundant free iron resulting from recurrent hemorrhage of endometrial cells within the cyst, which adversely affects ovarian funct…
other
2024
PURPOSE: To elucidatethe epigenetic alteration associated with impaired oogenesis in endometrioma using multi-omic approaches. METHODS: ATAC-seq was performed on the granulosa cells (GCs) of 6 patients (3 with endometrioma and 3 without). …
lab-animal
2023
Iron is essential for the health of reproductive system, and women with iron overload suffer from ovarian dysfunction and lack effective treatment in fertility preservation. However, the underlying mechanism of the detrimental effects of ir…
rct
2022
PURPOSE: This study aimed to develop a predictive tool for live birth in women with adenomyosis undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatment. METHODS: A total of 424 patients with adenomyosis wh…
review
2022
Recurrent pregnancy loss (RPL) has become an important reproductive health issue worldwide. RPL affects about 2%-3% of reproductive-aged women, and makes serious threats to women's physical and mental health. However, the etiology of approx…
observational
2021
Abstract Background There is few predictive tools for live birth in women with adenomyosis, which provide further personalized and clinically specific information related to individualized decisions making during IVF/ICSI treatment. Methods…