Carlo Bulletti

PURPOSE: Does fertility preservation (FP) through oocyte cryopreservation provide realistic reproductive opportunities for diminished ovarian reserve (DOR)? Literature suggests cumulative live birth rates of 30-45% with 8-10 oocytes under 3…

All analyses were conducted using RevMan 5.4 and R.Sensitivity analysis Meta-analysis was performed using a random-effects model to account for interstudy variability.Heterogeneity was assessed with the I statistic.For each comparison group…

Objective: To provide a rigorous, multidisciplinary synthesis of the epidemiological, genetic, immunological, and environmental factors contributing to Premature Ovarian Failure (POF), with particular attention to regional disparities, occu…

BACKGROUND: Infertility affects around 17.5% of reproductive-aged individuals worldwide, posing significant personal and public health challenges. Although Medically Assisted Reproduction and Assisted Reproductive Technology (ART; e.g., in …

The aim of this systematic review was to identify clinical decision support algorithms (CDSAs) proposed for assisted reproductive technologies (ARTs) and to evaluate their effectiveness in improving ART cycles at every stage vs traditional …

Endometriosis affects around 10% of reproductive-age women, causing severe pain, infertility, and various other symptoms. Traditional treatments, like hormonal therapies and surgeries, often provide temporary relief with significant side ef…

Progesterone is the ovarian steroid produced by the granulosa cells of follicles after the LH peak at mid-cycle. Its role is to sustain embryo endometrial implantation and ongoing pregnancy. Other biological effects of progesterone may exer…

Endometriosis - a disease causing pain and infertility - is encountered in nearly 50% of infertile women. While medical treatment is effective on pain and recurrence of symptoms after surgical excision, it is of no help for treating inferti…

OBJECTIVE: Endometriosis is a frequent indication for in vitro fertilization and embryo transfer (IVF-ET). Its influence on IVF-ET cycles remains controversial. We evaluated the impact of the severity of endometriosis on IVF-ET cycles in yo…

BACKGROUND: Questions remain as to whether surgical excision of ovarian endometriomas might cause damage to ovarian function. To test the hypothesis that ovarian surgery for endometrioma compromises ovarian function and accelerates ovarian …

The incidence of endometriosis among women with dysmenorrhea is 40% to 60% and those with subfertility is 20% to 30%. After surgical treatment of endometriosis, recurrence is common, with an estimated rate of 4.6% to 31%. The primary concer…

Endometriosis is a debilitating condition characterized by high recurrence rates. The etiology and pathogenesis remain unclear. Typically, endometriosis causes pain and infertility, although 20-25% of patients are asymptomatic. The principa…

OBJECTIVE: To evaluate the role of parturition in the recurrence of endometriosis. DESIGN: Retrospectively analyzed, prospectively obtained data. SETTING: Unit of Physiopathology of Reproduction, Health Care Unit of Rimini, and University…

Infertile women are examined to exclude tubal occlusion or a pelvic factor through indirect tests, such as hysterosalpingography (HSG), sonohysterosalpingography/hysterosalpingosonography (SH), and/or laparoscopy (Lps). Assisted reproductiv…

PURPOSE OF REVIEW: The aim of this article is to assess the importance of uterine contractility in the implantation of human embryos. RECENT FINDINGS: Recent findings show that the receptive phase of the endometrium seems to occur in close…

The receptive phase of the endometrium seems to occur in close association with the appearance of pinopodes and endometrial integrins that may be activated by the interleukin-1 system (IL-1). Embryo attachment is the result of adhesion prot…

PURPOSE OF REVIEW: The aim of this article is to assess the importance of uterine contractility in the implantation of human embryos. RECENT FINDINGS: Recent findings show that the receptive phase of the endometrium seems to occur in close…

The nonpregnant uterus shows uterine activity throughout the menstrual cycle. This uterine activity was detected both by single strep tissue and by using intrauterine pressure recordings in vitro and in vivo. Today, ultrasound has made it p…

OBJECTIVE: To establish the role of uterine contractions in retrograde menstruation with subsequent abdominal implantation of endometrial tissue. DESIGN: Controlled prospective study. SETTING: University hospital-based study. PATIENT(S):…

Bulletti, Carlo; DeZiegler, Dominique; Stefanetti, Marco; Cincinelli, Ettore; Pelosi, Emanuele; Flamigni, Carlo

Recent renewed interest in uterine contractility stems from the possibility of directly visualizing uterine contractility on images generated by high-resolution ultrasound probes. During the menstrual cycle, three typical patterns of uterin…

BACKGROUND: The present study was undertaken to evaluate differences between patients with and without eutopic endometrium in the recurrence of ectopic endometriotic implants. METHODS: Endometrial ablation (EA) was carried out in 14 women …