MyeongJin Yi

ORCID: 0000-0002-6561-3620 · 3 papers in corpus
lab-animal 2026
Deciphering estrogen receptor alpha-driven transcription in human endometrial stromal cells via transcriptome, cistrome, and integration with chromatin landscape
F&S science ·doi:10.1016/j.xfss.2025.08.002

OBJECTIVE: To investigate estrogen receptor gene 1 (ESR1) and estrogen-driven transcription in human endometrial stromal cells. DESIGN: RNA sequencing (RNA-seq) and Cleavage Under Targets and Release Using Nuclease (Cut&Run) were performed…

lab-animal 2025
Progesterone receptor isoform modulation via enhancer activation regulates progesterone signaling in endometrial stromal cells
F&S science ·doi:10.1016/j.xfss.2025.08.004

OBJECTIVE: To investigate enhancer-mediated regulation of progesterone receptor (PGR) isoforms, PGR-A and PGR-B, in human endometrial stromal cells, and to determine how isoform modulation shapes the progesterone-responsive transcriptome an…

lab-animal 2025
Transcriptional coregulator ZMIZ1 modulates estrogen responses that are essential for healthy endometrial function
The Journal of clinical investigation ·doi:10.1172/jci193212

Estrogen is a critical regulator of endometrial health. Aberrant estrogen stimulation can result in infertility, endometrial cancer, and endometriosis. Here, we identified Zinc Finger MIZ-Type Containing 1 (Zmiz1) as a coregulator of uterin…