Tan C

BACKGROUND: Heavy menstrual bleeding (HMB) is a common and debilitating condition in women with bleeding disorders (BD). The underlying hemostatic abnormalities in these patients often make standard treatments ineffective. Clinical manageme…

BACKGROUND: Melasma, a condition with complex and multifactorial pathogenesis, has traditionally been linked to factors such as ultraviolet (UV) exposure, hormonal changes, and genetic predisposition. Despite societal advances and shifts in…

OBJECTIVE: Effective early diagnosis and timely intervention in acute pancreatitis (AP) are essential for improving patient outcomes. This study aims to evaluate the clinical utility of the neutrophil CD64 index (nCD64) in stratifying patie…

OBJECTIVE: To assess the impact of lymphadenectomy on the survival of patients with stage I ovarian clear cell carcinoma (OCCC). METHODS: The records of 93 patients with stage I OCCC treated between January 2012 and December 2019 were revi…

INTRODUCTION: Ovarian cancer is one of the most fatal malignancies of the female reproductive system. The purpose of this study is to explore the mechanism of Actin Related Protein 2/3 Complex Subunit 1B(ARPC1B) in the progression of ovaria…

Background: Infertility is a global health concern. MEIOB has been found to be associated with premature ovarian insufficiency (POI) and non-obstructive azoospermia (NOA), but its variants have not been reported in Chinese patients. The aim…

FET is to resuscitate the endometrium and transfer the embryo into the uterus after the endometrium is ready. The quality of transferred embryos is an important factor affecting the outcome of assisted reproductive technology. This paper ai…

Breast cancer is the most commonly diagnosed cancer in women and approximately 33% of survivors will develop lymphedema. Untreated lymphedema may be limb threatening or cause substantial functional limitations. The purpose of this case repo…

OBJECTIVE: To investigate the mechanism of LncRNA H19 in Th17 cell differentiation and endometrial stromal cells (ESCs) proliferation in endometriosis (EMS). METHODS: LncRNA H19, miR-342-3p and IER3 expressions were detected by qRT-PCR and…

STUDY QUESTION: Are melatonin receptors (melatonin receptor 1A (MR1A) and melatonin receptor 1B (MR1B)) expressed in human endometrium and endometriotic tissue, and does melatonin affect endometrial cell proliferation? SUMMARY ANSWER: Mela…

AIM: This study assesses a clinical potential of immediate early responsive gene X-1 (IEX-1), also named IER3, in the diagnosis of epithelial ovarian carcinoma using blood and salivary specimens. METHODS: Immediate early responsive gene X-…

Chlamydia trachomatis polymorphic membrane proteins (Pmps) may increase genital tract inflammation and play a role in virulence. Antibody levels for PmpA, PmpD, and PmpI, measured in densitometric units, were assessed among a pilot sample o…