Octavio P. Luzardo

ORCID: 0000-0002-4153-3028 · 5 papers in corpus
other 2024
Effect of bariatric surgery in the body burden of persistent and non-persistent pollutants: longitudinal study in a cohort of morbidly obese patients
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1412261

INTRODUCTION: Obesity is a pathological state that involves the dysregulation of different metabolic pathways and adipose tissue cells, constituting a risk factor for the development of other diseases. Bariatric surgery is the most effectiv…

lab-animal 2000
Photoaffinity labeling identification of a specific binding protein for the anabolic steroids stanozolol and danazol: an oligomeric protein regulated by age, pituitary hormones, and ethinyl estradiol
Endocrinology ·doi:10.1210/endo.141.9.7667

We have demonstrated previously that both rat and human liver microsomes contain a highly specific binding protein for the anabolic steroids stanozolol (ST) and danazol (DA). In this study we solubilized the male rat liver ST-binding protei…

lab-animal 2000
Photoaffinity Labeling Identification of a Specific Binding Protein for the Anabolic Steroids Stanozolol and Danazol: An Oligomeric Protein Regulated by Age, Pituitary Hormones, and Ethinyl Estradiol
·doi:10.1210/en.141.9.3377

We have demonstrated previously that both rat and human liver microsomes contain a highly specific binding protein for the anabolic steroids stanozolol (ST) and danazol (DA). In this study we solubilized the male rat liver ST-binding protei…

lab-animal 1996
Identification of a specific binding site for the anabolic steroid stanozolol in male rat liver microsomes
The Journal of pharmacology and experimental therapeutics ·doi:10.1016/s0022-3565(25)21269-1

Male rat liver microsomes contain a [3H]dexamethasone binding site, capable of binding glucocorticoids and progesterone. We have shown previously that the 17 alpha-alkylated androgen, stanozolol, can inhibit the [3H]dexamethasone binding to…

lab-animal 1995
[3H]dexamethasone binding activity in liver microsomes is modulated differently by 17 alpha-alkylated androgens and testosterone in vivo
Pharmacology & toxicology ·doi:10.1111/j.1600-0773.1995.tb01025.x

Rat liver microsomes contain a single class of steroid binding sites, capable of binding various glucocorticoids and progesterone. In a previous article, we have described the in vitro interaction of several androgens with this binding site…