Boxian Huang

ORCID: 0000-0001-9913-9077 · 6 papers in corpus
lab-animal 2026
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202524090

Recurrent implantation failure (RIF), characterized by repeated failure to achieve clinical pregnancy after embryo transfer, is often associated with abnormal endometrial conditions. However, unexplained RIF is unique in that its underlying…

lab-animal 2026
Communications biology ·doi:10.1038/s42003-026-10247-3

Endometrial receptivity is essential for implantation and pregnancy, yet the role of the m6A demethylase FTO remains unclear. We examined epithelial Fto and Wnt signaling during the implantation window using CRISPR/Cas9 Fto knockout mice an…

lab-animal 2025
Communications biology ·doi:10.1038/s42003-025-07667-y

The regulatory mechanism between N6-methyladenosine (m6A) RNA methylation and histone modification in endometrial receptivity remains poorly understood. In this study, we depict that RIF induced m6A and Mettl3 level restrain, affecting H3K2…

lab-animal 2025
Aging cell ·doi:10.1111/acel.14376

The versatile epigenetic modification known as N6-methyladenosine (m6A) has been demonstrated to be pivotal in numerous physiological and pathological contexts. Nonetheless, the precise regulatory mechanisms linking m6A to histone modificat…

review 2024
Heliyon ·doi:10.1016/j.heliyon.2023.e23271

Premature ovarian insufficiency (POI) has far-reaching consequences on women's life quality. Due to the lack of full recognition of the etiology and complexity of this disease, there is no appropriate treatment for infected patients. Recent…

observational 2021
BMC pregnancy and childbirth ·doi:10.1186/s12884-021-04202-9

BACKGROUND: Psychological distress may exert a negative influence on reproductive function of couples at reproductive age. Couples seeking assisted reproductive technology (ART) treatment may have a higher prevalence of psychological distre…