Takashi Takahashi

ORCID: 0000-0003-0615-7001 · 3 papers in corpus
observational 2020
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
Nature genetics ·doi:10.1038/s41588-020-0640-3

The overwhelming majority of participants in current genetic studies are of European ancestry. To elucidate disease biology in the East Asian population, we conducted a genome-wide association study (GWAS) with 212,453 Japanese individuals …

other 2013
Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis
PloS one ·doi:10.1371/journal.pone.0057724

Clear cell adenocarcinoma of the ovary (OCC) is a chemo-resistant tumor with a relatively poor prognosis and is frequently associated with endometriosis. Although it is assumed that oxidative stress plays some role in the malignant transfor…

lab-animal 2012
The ferroimmunomodulatory role of ectopic endometriotic stromal cells in ovarian endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.04.047

OBJECTIVE: To understand the role of ectopic endometriotic stromal cells in ovarian endometriosis (OEM) and the associated risks for infertility and carcinogenesis. DESIGN: Analyses of secreted proteins and gene expression using immortaliz…