OBJECTIVES: This study evaluated the efficacy of individualized follitropin delta dosing in patients with potential low response, defined by anti-Müllerian hormone (AMH) level <9 pmol/L, undergoing ovarian stimulation for assisted reproduct…
STUDY QUESTION: What number of oocytes retrieved is associated with the highest cumulative live birth rates (CLBRs) in the fresh and subsequent frozen cycles following ovarian stimulation with follitropin delta? SUMMARY ANSWER: The CLBR in…
STUDY QUESTION: How do ovarian responses using conventional dosing for follitropin delta 15 µg/day compare with follitropin alfa 225 IU/day in women undergoing ovarian stimulation? SUMMARY ANSWER: The ADAPT-1 trial demonstrates similar ova…
STUDY QUESTION: How does a gonadotrophin-releasing hormone (GnRH) agonist versus a GnRH antagonist protocol affect ovarian response when using an individualized fixed daily dose of follitropin delta for ovarian stimulation? SUMMARY ANSWER:…
BACKGROUND: The American Society for Reproductive Medicine (ASRM) and the European Society of Human Reproduction and Embryology (ESHRE) are the two largest societies in the world whose members comprise the major experts and professionals wo…