Angela Santoro

ORCID: 0000-0002-6964-5152 · 20 papers in corpus
review 2026
Cancers ·doi:10.3390/cancers18172748

This review examines the clinical and practical implications of embedding molecular profiles directly into the 2023 FIGO staging system for endometrial carcinoma, in the context of the 2025 ESGO/ESTRO/ESP guidelines. The primary purpose is …

case-report 2025
International journal of molecular sciences ·doi:10.3390/ijms26115245

Mesonephric-like adenocarcinoma (MLA) of ovaries is a new and rare neoplastic entity, recently classified by the World Health Organization. Its morphological and immunohistochemical profile is similar to primitive cervical mesonephric adeno…

observational 2025
Facts, views & vision in ObGyn ·doi:10.52054/FVVO.2025.183

Hysteroscopic metroplasty improves reproductive outcomes in women with a dysmorphic uterus, but the impact of adenomyosis in these patients is uncertain. We retrospectively analysed 69 women who underwent metroplasty for a dysmorphic uterus…

case-report 2025
Pathologica ·doi:10.32074/1591-951X-1221

The AFF2 gene encodes a protein involved in transcriptional regulation and chromatin remodeling. While primarily associated with Fragile X syndrome, AFF2 fusions have recently been identified in certain malignancies, mostly sinonasal squamo…

other 2025
Virchows Archiv : an international journal of pathology ·doi:10.1007/s00428-024-03743-6

Sex cord-like endometrioid carcinoma (SCLEC) is an uncommon entity which may constitute a diagnostic challenge. This study aimed to perform a clinicopathological, immunohistochemical, and molecular reappraisal of ovarian SCLEC. Consecutive …

other 2024
Virchows Archiv : an international journal of pathology ·doi:10.1007/s00428-023-03672-w
case-report 2023
Pathology, research and practice ·doi:10.1016/j.prp.2023.155062

HPV-independent in situ adenocarcinomas have been only recently added to the WHO 2020 classification. To date, little information has been published about HPVindependent precursor lesions. In particular, regardiong the extremely rare cervic…

other 2023
Virchows Archiv : an international journal of pathology ·doi:10.1007/s00428-023-03659-7
meta-analysis 2023
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1136/ijgc-2022-004014

OBJECTIVE: In endometrial carcinoma patients, sentinel lymph node bilateral mapping fails in 20-25% of cases, with several factors affecting the likelihood of detection. However, pooled data about predictive factors of failure are lacking. …

review 2023
Biomedicines ·doi:10.3390/biomedicines11061714

Chronic endometritis (CE) is the persistent inflammation of the endometrial lining associated with infertility and various forms of reproductive failures. The diagnosis of CE is based on the histological evidence of stromal plasma cells; ho…

meta-analysis 2022
Pathobiology : journal of immunopathology, molecular and cellular biology ·doi:10.1159/000521105

BACKGROUND: A better endometrial cancer (EC) prognosis in patients with coexistent adenomyosis has been hypothesized based on a different prevalence of favorable EC histological prognostic factors. However, pooled risk of EC unfavorable his…

case-report 2022
Diagnostics (Basel, Switzerland) ·doi:10.3390/diagnostics12123146

Pilomatrix-like high-grade endometrioid carcinoma (PiMHEC) has recently been described as an aggressive variant of endometrial carcinoma. Herein, we described a case of ovarian PiMHEC, comparing it to endometrial PiMHEC and assessing previo…

meta-analysis 2022
·doi:10.6084/m9.figshare.18741077

Background: A better endometrial cancer (EC) prognosis in patients with coexistent adenomyosis has been hypothesized based on a different prevalence of favorable EC histological prognostic factors. However, pooled risk of EC unfavorable his…

other 2021
Diagnostics (Basel, Switzerland) ·doi:10.3390/diagnostics11040713

BACKGROUND: To date, useful diagnostic applications of p16 IHC have been documented in gynecological pathology both for HPV-related and non-HPV-related lesions. In the present article, we reported our experience with the novel anti-p16 INK4…

review 2021
Cancers ·doi:10.3390/cancers13194918

A better endometrial cancer (EC) prognosis in patients with coexistent adenomyosis has been reported. Unfortunately, it is still unclear if this better prognosis is related to a more favorable clinical profile of adenomyosis patients. We ai…

meta-analysis 2021
International Journal of Gynecology & Obstetrics ·doi:10.1002/ijgo.13818

BACKGROUND: Despite the high prevalence of adenomyosis in hysterectomy specimens of endometrial carcinoma (EC) patients, the relationship between adenomyosis and EC prognosis appears unclear. OBJECTIVE: To assess the prognostic value of co…

2021
case-report 2020
Gynecologic and obstetric investigation ·doi:10.1159/000508225

INTRODUCTION: Endometriosis is a common benign gynecological condition that can be associated with a slightly increased risk of developing a wide range of malignancies. CASE PRESENTATION: We herein report a singular case of a 62-year-old w…

other 2019
BMC cancer ·doi:10.1186/s12885-019-6318-5

BACKGROUND: The aim of this study was to assess the agreement rate between intraoperative evaluation (IOE) and final diagnosis (FD) in a series of surgically resected endometrial carcinoma (EC), with a preoperative ambiguous or inconclusive…

meta-analysis 2011
Archives of gynecology and obstetrics ·doi:10.1007/s00404-010-1700-1

INTRODUCTION: Endosalpingiosis is a disorder of Mullerian system characterized by benign glands lined by tubal type epithelium and involves the peritoneum, subperitoneal tissues, and retroperitoneal lymph nodes. Endosalpingiosis is almost a…