Johnny S. Younis

Ovarian endometriomas are commonly assessed according to cyst size and laterality, anatomical features that have long been regarded as indicators of disease severity and potential ovarian compromise. Consequently, these characteristics have…

STUDY QUESTION: Is endometrioma diameter associated with ovarian reserve, as reflected by serum anti-Müllerian hormone (AMH) levels, in women of reproductive age with no history of ovarian surgery? SUMMARY ANSWER: Across 30 independent coh…

Endometriomas are a common manifestation of endometriosis in women of reproductive age and pose a clinical challenge due to their association with pain, infertility, and compromised ovarian reserve. Surgical removal through cystectomy remai…

BACKGROUND: Evidence suggests that endometrioma cystectomy can significantly reduce ovarian reserve. Ethanol sclerotherapy is a promising, minimally invasive alternative. This overview aims to critically evaluate systematic reviews that add…

Endometriosis-associated ovarian cancer (EAOC) is an evolving clinical entity believed to develop from ovarian endometriosis.Continuous efforts are nowadays invested in exploring its pathogenesis and causality.Since endometrioma is a widesp…

Large-scale studies show endometriosis linked to earlier menopause onset. Recent research targeting women with laparoscopically diagnosed endometriosis found an increase in cases of early natural menopause. Furthermore, recent large-scale c…

Currently, three crucial questions regarding the reliability of ovarian reserve measures in women with ovarian endometrioma during the reproductive age are being discussed. Firstly, the effects of endometriotic cystectomy on short and long-…

By Johnny Younis. In this in-depth video, Prof. Johnny Younis, from Israel, takes the audience on a profound exploration of the intricate relationship between endometriosis and the potential development of ovarian cancer.

OPINION article Front. Oncol., 23 May 2023Sec. Gynecological Oncology Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1193123

Endometriosis-associated ovarian cancer (EAOC) is an evolving clinical entity believed to develop from ovarian endometriosis. Continuous efforts are nowadays invested in exploring its pathogenesis and causality. Since endometrioma is a wide…

Endometriosis is a chronic, universal, and prevalent disease estimated to affect up to 1:10 women of reproductive age. Endometriosis-associated ovarian cancer (EAOC) developing at reproductive age is challenging and of concern for women and…

OPINION article Front. Endocrinol., 30 June 2022Sec. Reproduction https://doi.org/10.3389/fendo.2022.921032

OPINION article Front. Endocrinol., 21 September 2022Sec. Reproduction Volume 13 - 2022 | https://doi.org/10.3389/fendo.2022.996531

OPINION article Front. Endocrinol., 10 November 2022Sec. Reproduction Volume 13 - 2022 | https://doi.org/10.3389/fendo.2022.1005597

Women with endometriosis, especially those with endometrioma, present a considerable challenge for ovarian reserve appraisal. This diagnostic difficulty arises from several fundamental questions inherently linked to patient management: the …

OBJECTIVE: Accurate preoperative counseling about whether an endometriotic cystectomy has a detrimental effect on the ovarian reserve has been a considerable challenge, because studies assessing the postoperative antral follicle counts and …

RESEARCH QUESTION: Is there a difference in ovarian reserve biomarkers and ovarian response between the right and left ovaries of infertile women undergoing IVF treatments? DESIGN: A total of 100 infertile women aged 27 to 37 years, diagno…

PURPOSE: To investigate whether unexplained infertility at a young age demonstrates manifestations of decreased ovarian reserve. METHODS: A total of 100 women were divided into two equally sized groups. The study group comprised women aged…

BACKGROUND: Ovarian endometrioma is a frequent manifestation of endometriosis in women of reproductive age. Several issues related to its space occupying effects, local reactions and surgical removal continue to be actively debated today. T…

PURPOSE: To investigate the occurrence of multinucleated blastomeres (MNB) in poor ovarian response (POR) women defined under the Bologna criteria. METHODS: This observational study was designed in a prospective controlled manner. Among 38…

Postponement of child bearing and maternal age at first pregnancy are on the rise, contributing considerably to an increase in age-related infertility and the demand for assisted reproductive technologies (ART) treatment. This brings to the…